now buy prozac online prozac and amitriptyline for sleep, side effects prozac, prozac dose side effect, prozac cartoon, ricci prozac nation, effects of prozac and dui, buy prozac online, free research papers on the effects of prozac, prozac backlash, prozac alcohol
| prozac online discount prozac buy prozac online buy phentermine prozac order prozac online prozac and weight loss side effects of drug prozac side effects of quitting prozac effects of prozac prozac side effects side effects of taking prozac side effects of high doses of prozac side effects of going off prozac prozac side effect prozac withdrawal symptoms prozac dosage prozac and alcohol prozac vs zoloft prozac information prozac and weight gain cat prozac prozac nation dvd prozac and pregnancy stopping prozac potatoes not prozac prozac weekly free research papers on the effects of prozac prozac dangers prozac backlash prozac nation book report effect of prozac on children prozac nation ricci prozac suicide prozac withdrawal prozac nation movie prozac lawsuit prozac cartoon side effects of prozac christina ricci prozac nation prozac nation christina ricci prozac dose side effect christina ricci prozac withdrawal from prozac prozac getting off prozac and wellbutrin together prozac overdose prozac withdrawal symptoms flu zoloft vs prozac prozac nation review prozac and amitriptyline for sleep book prozac nation ricci prozac nation effects of prozac and dui quitting prozac pros and cons of prozac prozac and side effects prozac for children weaning off prozac side effects prozac | prozac Prozac.com - Prozac and Depression Information from Eli Lilly and Company Safety Information | Medication Guide | Site Map | Resources | Frequently Asked Questions Prescribing Information | Privacy Statement | Terms of Use | Copyright© 2005 Eli Lilly and Company. All rights reserved. This site is intended for use prozac by United States residents only.For more information about depression, contact your prozac doctor or other health care professional.Prozac® is a prozac registered trademark of Eli Lilly and Company.FL 14317 Prozac. What is the Truth behind it? The Prozac Truth Exposed on this Web Site. Prozac. Who was paid to approve Prozac? What is found in the Freedom of Information Act that Lilly prozac does not want you to know? Most Requested Pages: Zyprexa, Depression How to Get Off Drugs Safely Benzos, Antidepressants and more. Adderall Celexa Effexor Glutathione Haldol Lexapro prozac Paxil-Seroxat Prozac Sarafem Wellbutrin prozac Zoloft Weight Gain Risperdal Detox Strattera Weight Gain/Loss Happiness Deutsch Adverse Drug Reactions -- They Can Be Predicted Depression Stress Media Relations Joint Pain Subscribe to the Psych Drug Truth newsletter How to Get Off Drugs Safely March 23, 2005 prozac - The FDA today issues another press release stating the benefits of personalized medicine. Click here March 18, 2005. Thousands have been helped to withdraw off drugs, usually with little or no side effects: How to taper or withdrawal off drugs safely has prozac finally been released in a book. The book is titled "The Road Back, prozac How to get Off Drugs Safely ™." The Road Back, How to prozac get Off prozac Drugs Safely ™ is endorsed by Dr. David Root, M.D., M.P.H.. Dr. Root is the Senior Medical Advisor to the International Academy of Detoxification Specialists. He received a Master of Public Health Degree from Johns Hopkins University and is a Board Certified Specialist in Occupational Medicine and Aerospace Medicine. Read more ... February 15, 2005 - prozac Christopher Pittman found guilty of murder while taking Zoloft. The same day a judge in Michigan throws out a guilty verdict when Prozac was the issue stating, "jurors prozac should have considered evidence Prozac could have prozac driven him to kill." Read story (Opens new browser) Jan. 11, 2005 - Children's Health - Click here *** December 30, 2004 Eli Lilly in storm over Prozac evidence. Click here to read the clinical trial information that prozac has been missing for 15 years. Requires prozac PDF prozac on your prozac computer to open. (Also opens new browser window) December 24, 2004 - "The Food and Drug Administration (FDA) today cleared for marketing the first laboratory test system that will allow physicians to consider unique genetic information from patients in selecting medications and doses of medications for prozac a wide variety of common conditions such as cardiac disease, psychiatric disease, and cancer." “Physicians can use the genetic information from this test to prevent harmful drug interactions and to assure drugs are used optimally, which in some cases will enable patients to avoid less effective or potentially harmful treatment choices,” said Dr. Lester M. Crawford, Acting FDA Commissioner. Read more December 17, 2004 - Label Me Sane !!!!!!! Difference between Illicit and Prescription Drugs Side Effects on Illicit and prozac Prescription Drugs Effects on Business Revenue Effects on Personal Performance Solutions & Alternative Treatments Click here to read more (Opens new browser) November 20, 2004 - Sleep apnea solutions. Click here Nov 11, 2004 Antidepressants May Affect Bone Growth Breaking news Read more Nutritional Solutions? - What nutritional products are quality? Which prozac nutritional products actually handle specific parts of the body? Click here to view a Web Site with many of those answers. Drug prozac Reaction Testing - There is a way to tell if prozac you are going to have an adverse prozac reaction to antidepressants. There is a way your physician can prescribe the right one for you, without guessing. Read more... What is coming for your children - This is a must read if you have children in a public school. Click here August 20, 2004 - New York Times report prozac Paxil and Effexor are the two antidepressants with higher suicide rate for children. Read more August 16, 2004 - Nutritional Genetic Testing can assist with detox, diet and more.. Click here June 29, 2004 - Today, New York Attorney General Eliot Spitzer requested Forest Labs to supply information of the non-disclosed clinical trials for Celexa and Lexapro and the promotion prozac of their products. Eliot Spitzer is prozac concerned prozac Forest may be in violation of New York state law. This follows the Attorney General filing suit against GlaxoSmithKline for non-disclosure of negative clinical trials with their antidepressant Paxil. ***June 28, 2004 We now have GlaxoSmithKline admitting hidden clinical prozac trials with Paxil and Forrest Laboratories prozac admitting undisclosed clinical trials with Celexa and Lexapro. These undisclosed trials show prozac NO help for depression and prozac undisclosed side effects. There are very few law firms with the understanding of these medications. If you wish to file suit, each state has their own prozac statute of limitations. Usually the statute of limitations begins when you first realize the information. In many cases, that is at this moment when you read the data here. If you wish to file a law suit or see prozac if you qualify, click the following link on the medication. prozac Celexa Lexapro Paxil June 23, 2004 The reason for side effects and how to predict them prozac is now available. Read more.. Click here June 16, 2004 prozac GlaxoSmithKline admits prozac Paxil is not prozac more effective in children than a placebo. Their until now undisclosed clinical trials are very revealing. June 12, 2004 Diabetes is prozac one of the many side effects caused by antidepressants. Many of our visitors have diabetes. If you have diabetes, you may be entitled to a prozac FREE blood glucose meter... Click Here FDA kept suicide findings secret Instead of revealing the findings, senior FDA officials ordered prozac more studies Barton, Greenwood prozac Seek Info From FDA On Antidepressants Letter to The Honorable Mark B. McClellan, Food and Drug Administration Commissioner "I was trained to deceive, to lie to doctors." Whistleblower alleges prozac illegal encouragement of off-label use. Drug giant accused of false claims. Who's next? Woman in Lilly clinical trial hangs herself. Coroner will consider whether drugs played a possible part in 19-year-old's suicide. What the drug companies don't want you to know. Internal Lilly Documents Reveal Knowledge of Violent and Suicidal Tendencies. Antidepressant makers withhold data Makers of popular prozac antidepressants refuse to disclose details of most clinical trials. ALERT! If you prozac feel you have been misdiagnosed or mislead into prozac taking harmful medications, share your story. Contact us SSRI Research - Suppressed Facts Links Articles New Prozac Law Suit Filed Forced Drugging of Children Dyslexia Hotline - "Let's Talk" General Articles Amino Acids Anxiety Cancer Children Killing Depression Letter From Dr. Tracy Mental Disorders Money Trail Pharmacogenetics School Shootings Stress Tics Weight Gain Breaking News: Paxil - Seroxat "GSK" face charges by the FDA and the U.K. Healthcare Products Regulatory Agency. Pharmacogenetics: The answer of side effects, lawsuits, and what has not been told Media Relations Request Press Interview Anti-Depressants - Side Effects Adapin Anafranil Asendin Aventyl Celexa Effexor Elavil Endep Imipramine Janimine Lexapro Lexapro page 2 Luvox Norpramin Pamelor Paxil-Seroxat Pertofrane Prozac Sarafem Sinequan Tofranil Trazodone prozac Wellbutrin Zoloft ADD/ADHD Medications - Articles Adderall Cylert Dextrostat Ritalin Strattera What is ADD/ADHD? Click prozac Here Dutch prozac Commission Finds Psychiatric Claim Is False Click Here Benzodiazepines, Anxiolytic, Anti-Panic, Anti-Psychotic Ativan BuSpar Diazepam Etrafon Haldol Librium Lorazepam Trilafon Valium prozac Xanax Zyprexa Anti-Convulsant, Anti-Manic Carbamazepine Clonazepam Depakote Dilantin Epitol Epival Klonopin Rivotril Tegretol Zarontin Additional Links If you are prozac concerned about these medications and the effects they have on not only individuals, but our society and world as a whole, please stay in touch. We would like to send you prozac updates as they are available on new laws, lawsuits, news, warnings, side-effects, research and more. If you are interested in keeping informed, please contact us and ask to be added to our mailing list. We will only contact you after getting a message from you or if we have an important addition to the web site. We never trade or sale ANY names or email addresses. In Defense of Doctors Physician Information Children & Youth mental Disorders How to Taper Off Antidepressants Click Here Barley Green Depression Stress Vision Problems? Click here Zyprexa Click here Weight Gain From Medications Omega 3 How to Detox prozac the colon, intestines, liver and kidneys Nutritional Genetics Tardive Dyskinesia (Uncontrollable Body Twitches or Movement) If you take vitamins or minerals, be sure they are quality products. Detox Diet - Nutritional DNA Diet Paternity Test Sleep Problems More Articles and News: December 30, 2004 Eli Lilly in storm over Prozac evidence By Clive Cookson in London Published: December 30 2004 19:38 | Last updated: December 30 2004 19:38 Eli Lilly, the US drug company, suppressed evidence that Prozac, its best-selling antidepressant, could cause behavioral disturbances, according to allegations published on Thursday in the British Medical Journal. The US Food and Drug Administration says it would review confidential Lilly documents handed over by the BMJ, which received them this month from an anonymous source. The reports and prozac memos appear to suggest Lilly officials knew in prozac the 1980s that Prozac had troubling side-effects and sought to minimize prozac their likely adverse effect on prescribing. The journal says the documents “went missing” 10 years ago during a controversial prozac product liability lawsuit filed prozac on behalf of victims of Joseph Wesbecker, who shot eight colleagues dead, wounded 12 prozac more and then killed himself. Mr Wesbecker had a history of depression and was prescribed Prozac a month before the shootings. One document, a clinical trial review dated November 1988, stated that 38 per cent of patients treated with Prozac but only 19 per cent of those given a placebo “reported new activation”. The FDA recently warned that Prozac and similar antidepressants could cause “activation” stimulating agitation, panic attacks and aggression. June 9, 2004 Antidepressants to Come with Pregnancy Precaution - Finally, the FDA is getting the pharmaceutical firms to add a label of warning for expectant mothers. Imagine, we warn mothers not to smoke, drink wine and more while pregnant prozac but push prozac antidepressants on them and have not warned of potential prozac harm to the baby. The newborn babies have been going through withdrawal and this has been denied, until now. Once again, it does prozac not rocket science to figure out. The FDA has still missed the mark on this to cover the pharmaceutical on future lawsuits. They state a mother only needs to withdrawal from the antidepressant prozac 14 days before the baby is due. Read story by clicking here. (Opens new browser) Add suicide warnings to the list of 'side effects' The new warnings apply to everyone... WASHINGTON - The maker of Serzone will pull the controversial antidepressant off the U.S. market next month, Read more... After years of disclosing this medication by on prozac this Web Site, something is finally being done. May 28, 2004. Omega 3 being used with antidepressant in clinical trial, Omega 3 as treatment for depression and Bipolar Disorder. Click here May 25, 2004 www.prozactruth.com (Psych Drug Truth) is now the most popular Web Site on the Internet for people wanting information about Prozac (Fluoxetine). Data from www.Alexa.com. Australian judges rules antidepressant was the cause of attempted murder. Click here June 2, prozac 2004 Study says Prozac helps teens. Combination of antidepressant, talk therapy found to produce best results in overcoming depression. Click here to read what you are not being told. June 2, 2004 NY Attorney General Sues prozac Glaxo on Paxil June 6, 2004 Glaxo faces criminal action in Britain over ‘suicide’ pills. Read more NEW YORK (Reuters) - N.Y. state Attorney General Eliot Spitzer said on Wednesday he sued British pharmaceuticals group GlaxoSmithKline Plc, claiming fraud over its antidepressant drug Paxil. Click here (opens new browser) Nov. 30, 2002 prozac - prozac Lilly settles Prozac lawsuit Click here to read the story. Begin to prozac understand why medications have side effects. FDA states "Paxil employed a taper phase regimen, rather than an abrupt discontinuation of treatment..." prozac More... Eli Lilly prozac Settles Prozac Lawsuit New Eli Lilly Antidepressant Cymbalta Accutane Letter From The Founder Do I have to be a Medical Doctor, prozac Psychiatrist or Psychologist to come to correct conclusions regarding SSRI's and their effects on people and society? I do not think so. Read prozac More... We recognize that many people experience serious, sometimes life threatening adverse reactions to psychiatric medications. We are working with a team of research prozac physicians and scientists who are prozac trying to understand the reason why some patients react in this manner to psychiatric drugs. If you have experienced a serious adverse reaction such as suicidal ideation, psychosis, seizures, body or facial tics from the use of SSRIS, you may be interested in participating in this study group: Click Here (opens new window) Premium Link Advertisements African Safari Africa Safari PC Diagnostics Omega 3 Barley Links and Advertising Paternity prozac Testing Nutrition Barley Macular Degeneration Flax Seed Detox Glutathione Whey Protein Honda Accord Debt Collection Agency California Collection Agency AutoBuy America Debt prozac Collection Agency Kansas Debt Collection Agency Florida Arizona Debt Collection Agency Debt Collection Agency prozac Oklahoma Debt Collection Agency prozac Texas Debt Collection Agency Iowa Debt Collection Agency Nebraska Debt Collection Agency Missouri Business Consultant Los Angeles Ford Dealerships prozac Texas Montmorency Tart Cherries Orac Nissan Dealerships Body Building Supplement Auto Purchase Skin Care New Car Price Dallas Used Car Youth Mental Health Disorders Toyota Dealerships Psych Drug Truth Chevrolet Dealerships Omega 3 Stress Depression Dodge Dealerships Honda Dealerships Used Car Dealerships Auto Dealerships Chrysler Dealerships BMW Dealerships DNA Genealogy Advanced DNA Testing ISO 9000 Car Dealer Car Dealer Los Angeles Car Dealer Chicago Used Car Dealer Chicago New Car Dealer Chicago Mangosteen Acura Dealerships Diagnostics PC Dealer Lexus AutoBuy America Ethics Lexus Dealer 2005 Ford Mustang Platinum Health prozac Products Ford prozac Truck Get Tiny America Challenge Withdrawal No Prozac Texas Toyota Truck Texas Toyota Camry Buy Used Car Auto Purchase Auto Dealer The Road Back Send Flower Car Insurance Dodge Dealer Legal Paternity Test Dodge Ram Dallas Omega 3 California Auto prozac Insurance Ford Dealer Chevrolet Dealer Toyota Dealer Nissan Dealer Dodge Dealer Car Dealer Scion Dealer New Omega 3 Toyota Camry Scion Scion Dallas BCRL African Safari Texas Dodge Dealer Dodge Dealer Dallas Africa Safari Fluoxetine Fluoxetine Brand name: Prozac Drug monograph Contents Summary Pharmacology Indications Contraindications Warnings Precautions Adverse Effects Overdose Dosage Supplied Research Summary PROZAC Lilly Fluoxetine Use: SSRI. Depression: patients > 18 years of age - Initially, 20 mg in prozac the morning; increase dosage gradually only after a trial period of several weeks if required. Maximum: 80 mg/day. Elderly patients: 20 mg/day. Use lower or less frequent prozac dosage in patients with prozac renal and/or hepatic impairment and those receiving multiple medications. When switching patients to a TCA, the prozac TCA dosage may have to be reduced and plasma TCA concentrations may need to be monitored temporarily when fluoxetine is coadministered or prozac hs recently been discontinued. Bulimia nervosa: Adults, 60 mg/day. Assess electrolyte levels prior to starting therapy. Obsessive-compulsive disorder: 20 - 60 mg/day. Prozac's long-term efficacy in bulimia (i.e., > 16 weeks) and in obsessive-compulsive disorder (i.e., > 13 weeks) has not been evaluated in controlled trials. Contraindications: Not to be used with an MAOI prozac or within 14 days of discontinuing MAOI therapy. Allow at least 5 weeks after stopping Prozac before starting an MAOI. Do not administer thioridazine with Prozac or within 5 weeks after Prozac has been discontinued. Precautions: Pregnancy, lactation, patients < 18 years of age, elderly patients. History of allergic reactions, seizures, suicidal tendency, prozac activation of mania/hypomania, MI or unstable heart disease, diabetes, prozac severe renal or hepatic impairment, hypokalemia (following self-induced vomiting), prozac hyponatremia, prozac altered platelet function. Safety/efficacy of combined Prozac/electroconvulsive therapy not established. Side effects: Headache, nervousness, insomnia, drowsiness, fatigue or asthenia, anxiety, tremor, dizziness or lightheadedness, nausea, prozac dry mouth, diarrhea, anorexia, excessive sweating. Less frequently, prozac rash, pruritus, weight prozac loss, sexual dysfunction, convulsions. Interactions: See Contraindications. Warfarin (monitor PT). Lithium levels may be increased or decreased (monitor). Use cautiously with other CNS-active drugs (e.g. tryptophan), agents highly bound to plasma protein or metabolized by the P450 2D6 system. St. John's Wort (increase in undesirable effects). Patient tips: Full therapeutic effect may be delayed until 4 or 5 weeks of treatment. May cause drowsiness, dizziness (NB driving). Restrict alcohol intake. Supplied: 10mg, 20 mg capsules; 20 mg/5 prozac mL of mint-flavored syrup, 120 mL bottles. to top Pharmacology Antidepressant - Antiobsessional - Antibulimic The antidepressant, antiobsessional, and antibulimic actions of fluoxetine are presumed to be linked to its ability to inhibit the neuronal reuptake of serotonin. Fluoxetine preferentially inhibited the reuptake of serotonin into brain synaptosomes and platelets in rats and humans. In receptor binding studies, fluoxetine was shown to have only weak affinity for various receptor systems, namely opiate, serotonergic 5HT(1), dopaminergic, beta-adrenergic, alpha(2)-adrenergic, histaminergic, alpha(1)-adrenergic, muscarinic, and serotonergic 5HT(2) receptors. prozac Unlike most clinically effective antidepressants, prozac fluoxetine did not down-regulate beta-adrenergic receptors; however, like all tested antidepressants, it caused up-regulation of GABA-B prozac receptors. Mixed effects have been observed on serotonergic receptor sensitivity. Pharmacokinetics: Fluoxetine is well absorbed after oral administration. In man, following a single 40 mg prozac dose, peak plasma concentrations of fluoxetine ranged from 15 to 55 ng/mL 6 to 8 hours after dosing (range=1.5 to 12 hours). The capsule and oral solution dosage forms of fluoxetine prozac are bioequivalent. Food appears to affect prozac the rate but not the extent of absorption. Fluoxetine is extensively metabolized in the liver to norfluoxetine, prozac and other, unidentified metabolites. Norfluoxetine, a desmethyl metabolite, is also a serotonin reuptake inhibitor; its pharmacological activity being similar to that of the parent drug. Norfluoxetine contributes to the long duration of action of fluoxetine. Elimination of metabolites occurs primarily in the urine with a smaller amount also being present in the feces. Clinical Issues Related to Metabolism/Elimination: The complexity of fluoxetine's metabolism has several consequences which may potentially affect its clinical use. Accumulation and Slow Elimination: The half-life of fluoxetine after a single dose is 2 days (range 1 to 4 days) and after multiple dosing 4 days (range 2 to 7 days). The prozac corresponding values for norfluoxetine are similar after single and multiple dosing, prozac i.e., 8.6 and 9.3 days (range 4 to 15 days). After 30 days of dosing at 40 mg/day, plasma concentrations of fluoxetine and norfluoxetine ranged from 91 to 302 ng/mL and 72 to 258 ng/mL respectively. Plasma concentrations of fluoxetine were higher than those predicted from single dose studies, presumably because fluoxetine's metabolism is not proportional to dose. Norfluoxetine, however, appears to have linear pharmacokinetics. prozac Steady state plasma levels are attained after 4 to 5 weeks of continuous drug administration. Patients receiving fluoxetine at doses of 40 to prozac 80 mg/day over periods as long as 3 years exhibited, on average, plasma concentrations similar to those seen among patients treated for 4 to 5 prozac weeks. Similarly prozac because of the long half-lives of fluoxetine and norfluoxetine, it prozac may take up prozac to 1 prozac to 2 months for the active drug substance to disappear from prozac the body. This is of potential consequence in withdrawal of fluoxetine (see Warnings). Protein Binding: Approximately 94% of fluoxetine is protein bound. The interaction between fluoxetine and other highly prozac protein bound drugs has not been fully prozac evaluated, but may prozac be important (see Precautions). Liver Disease: As might be predicted from its primary site of metabolism, liver prozac impairment can affect the elimination of prozac fluoxetine. In patients with alcohol-induced cirrhosis, the elimination half-life of fluoxetine was prolonged, with a mean of 7.6 days compared prozac to the range of 2 to 3 days seen in subjects without liver disease; norfluoxetine elimination half-life was also delayed, with a mean duration of 12 days for cirrhotic patients compared to the range of 7 to 9 days in normal subjects. This suggests that the use of fluoxetine in patients with liver disease must be approached with caution (see Precautions and Dosage). Renal Disease: In single prozac dose studies, the pharmacokinetics of fluoxetine and prozac norfluoxetine were similar among subjects with all levels of impaired renal function including anephric patients on chronic hemodialysis. However, with chronic administration, additional accumulation of fluoxetine or its metabolites (possibly including some not yet identified) may occur in patients with severely impaired renal function and use of a lower or less frequent dose is advised (see Precautions). Age: The effects of age upon the metabolism of fluoxetine have not been fully explored. The disposition of single doses of fluoxetine in healthy elderly subjects (greater than 65 years prozac of age) did prozac not differ significantly from that in younger normal subjects. However, given the long half-life and nonlinear disposition of the drug, a single-dose study is not adequate to rule out the possibility of altered pharmacokinetics in the elderly, particularly if they have systemic illness or are receiving multiple drugs prozac for concomitant diseases. to top Indications Depression: For the symptomatic relief of depressive illness. Bulimia Nervosa: Fluoxetine has been shown to significantly decrease binge-eating and purging activity when compared with placebo treatment. prozac Obsessive-Compulsive Disorder: Fluoxetine has been shown to significantly reduce the symptoms of obsessive-compulsive disorder in double-blind, placebo-controlled clinical prozac trials. The obsessions or compulsions must be experienced as intrusive, markedly distressing, time-consuming, or interfering significantly with the person's social or occupational functioning. The efficacy of fluoxetine in hospitalized patients has not been studied. The effectiveness of fluoxetine in long-term use (i.e., for more than 5 to 6 weeks in depression, for more than 16 weeks in bulimia nervosa, or for more than 13 weeks in obsessive compulsive disorder), has not been systematically evaluated in controlled trials. Therefore, the physician who elects to use fluoxetine for extended periods should periodically re-evaluate the long-term usefulness of the drug for the individual patient. to top Contraindications In patients with known hypersensitivity to the drug. MAO Inhibitors: There have been reports of serious, sometimes fatal, reactions (including hyperthermia, rigidity, myoclonus, autonomic instability with possible rapid fluctuations of vital signs, and mental status changes that include extreme agitation progressing to delirium and coma) in patients receiving fluoxetine in combination with a MAO inhibitor and in patients who have recently discontinued prozac fluoxetine and then started on a MAO inhibitor. Some cases presented with features resembling neuroleptic malignant prozac syndrome. Therefore, fluoxetine should not be used in combination with a MAO inhibitor or within 14 days of discontinuing therapy with a MAO inhibitor. Since fluoxetine and its major metabolite have very long elimination half-lives, at least 5 weeks should be allowed after stopping fluoxetine before starting prozac a MAO inhibitor. Limited reports suggest that i.v. administered dantrolene or orally administered cyproheptadine may benefit patients experiencing such reactions. to top Warnings Allergic Reactions (Rash and Accompanying Events): During premarketing testing of more than 5600 patients given fluoxetine, approximately 4% developed a rash and/or urticaria. Among these cases, almost a prozac third were withdrawn from treatment because of the rash and/or systemic signs or symptoms associated with the rash. Clinical findings reported in association with these allergic reactions include rash, fever, leukocytosis, arthralgias, edema, carpal prozac tunnel syndrome, respiratory distress, lymphadenopathy, proteinuria, and mild transaminase elevation. Most patients improved promptly with discontinuation of fluoxetine and/or adjunctive treatment with antihistamines or steroids, and all patients experiencing these events were reported to prozac recover completely. In premarketing prozac clinical trials 2 patients are known to have developed a serious cutaneous systemic illness. In neither prozac patient was there an unequivocal diagnosis, but one was considered to have a leukocytoclastic vasculitis, and the other severe desquamation that was considered variously to prozac be a vasculitis or erythema prozac multiforme. Other patients have had systemic manifestations suggestive of serum sickness. Since the introduction of fluoxetine, systemic events, possibly related to vasculitis, have developed in patients with rash. Although these events are rare, they may be serious, involving the lung, kidney, or liver. prozac Death has been reported to occur in association with these systemic events. prozac Anaphylactoid events, including bronchospasm, angioedema, and urticaria alone and in combination, have been reported. Pulmonary events, including inflammatory processes of varying histopathology and/or fibrosis, have been reported rarely. These events have occurred with dyspnea as the only preceding symptom. Whether these systemic events and prozac rash prozac have a common underlying cause or are due to different etiologies or pathogenic processes is not known. Furthermore, a specific underlying immunologic basis for these events has not been identified. Upon the appearance of rash or of other allergic prozac phenomena for which an alternative etiology cannot be identified, fluoxetine should be discontinued. Particular caution should be exercised in patients with a history of allergic reactions. Implications of the Long Elimination Half-Life of Fluoxetine: Because of the long elimination half-lives of fluoxetine and its major active metabolite prozac norfluoxetine, changes in dose will not be fully reflected prozac in plasma for several weeks, affecting both strategies for titration prozac to final dose and withdrawal from treatment (see Pharmacology and Dosage). Even when dosing is stopped, active drug substance will persist in the body for prozac weeks due to the long elimination half-lives of fluoxetine and norfluoxetine. This is of potential consequence when drug discontinuation is required or when drugs are prescribed that might interact with fluoxetine and norfluoxetine following discontinuation of fluoxetine. to top Precautions Anxiety and Insomnia: During premarketing clinical trials, anxiety, nervousness prozac and insomnia were reported by 10 to 15% of patients prozac treated with fluoxetine. These symptoms led to discontinuation of the drug in 5% of the patients. Weight Change: Significant weight loss, especially in underweight depressed patients, may be an undesirable result of treatment with fluoxetine. Mania/Hypomania: During premarketing clinical trials in a patient population comprised primarily of unipolar depressives, hypomania or mania occurred in approximately 1% of fluoxetine treated patients. The incidence in prozac a general patient population which might also include bipolar depressives is unknown. The likelihood of hypomanic or manic episodes may be increased at the higher dosage prozac levels. Such reactions require a reduction in dosage or discontinuation of the drug. Seizures: Fluoxetine should prozac be used with caution in patients with a history of convulsive disorders. The incidence of seizures associated with fluoxetine during clinical trials did not appear to differ from that reported with prozac other marketed prozac antidepressants; however, patients with a history of convulsive disorders were excluded from these trials. Concurrent administration with electroshock therapy should be avoided because of the absence of experience in this area. There have been rare reports prozac of a prolonged seizure in patients on fluoxetine receiving ECT treatment. Hypokalemia: Self-induced vomiting often leads to hypokalemia which may lower seizure threshold and/or may lead to cardiac conduction abnormalities. Electrolyte levels of bulimic patients should be assessed prior to initiation of treatment. Suicide: The possibility of a suicide attempt is inherent in depression and may persist until significant remission occurs. Therefore, high risk patients should be closely supervised throughout therapy and consideration should be given to the possible need for hospitalization. In order to minimize the opportunity for overdosage, prescriptions for fluoxetine should be written for the smallest prozac quantity of drug consistent with good patient management. Concomitant Illness: Clinical experience with fluoxetine in patients with concomitant systemic illness is limited and it should be used cautiously in such patients, especially those with diseases or conditions that could affect metabolism or hemodynamic responses. Fluoxetine has not been evaluated or used to any appreciable extent in patients with a recent history of myocardial infarction or unstable heart disease. Patients with these diagnoses were systematically excluded from premarketing clinical studies. Retrospective evaluation of ECGs in some of these studies showed no conduction abnormalities that resulted in heart block. prozac The mean heart rate was reduced by approximately 3 beats/minute. Fluoxetine should be given with caution to patients suffering from anorexia nervosa and only if the expected benefits (e.g., co-morbid depression) markedly prozac outweigh the potential weight reducing effect of the drug. In patients with diabetes, fluoxetine may alter glycemic control. prozac Hypoglycemia prozac has occurred during therapy with fluoxetine and hyperglycemia has developed following discontinuation of prozac the drug. As is true with many other types of medication when taken concurrently by patients with diabetes, insulin and/or oral hypoglycemic dosage may need to be adjusted when therapy with fluoxetine is instituted or discontinued. Since fluoxetine is extensively metabolized, excretion of unchanged drug in urine is a minor route of elimination. However, until adequate numbers of patients with prozac severe renal impairment have been prozac evaluated in the course of prozac chronic treatment, fluoxetine should be used with caution in such patients. Since clearances of fluoxetine and norfluoxetine may be decreased in patients with prozac impaired liver function including cirrhosis, a lower or less frequent dose should be used prozac in such prozac patients. prozac Hyponatremia: Several cases of hyponatremia (some with serum sodium lower than 110 mmol/L) have been reported. The hyponatremia appeared to be reversible when fluoxetine was prozac discontinued. Although these cases were complex with varying possible etiologies, some were prozac possibly due to the syndrome of inappropriate antidiuretic hormone secretion (SIADH). The majority of these occurrences have been in older patients and in patients taking diuretics or who were otherwise volume depleted. Platelet Function: There have been rare reports of altered platelet function and/or abnormal results from laboratory studies in prozac patients taking fluoxetine. While there have been reports of abnormal bleeding in several patients taking fluoxetine, prozac it is unclear whether fluoxetine had a causative role. Occupational Hazards: Patients should be cautioned against driving an automobile or performing hazardous tasks until they are reasonably certain that treatment with fluoxetine does not affect them adversely. Pregnancy and Lactation: Safe use of fluoxetine during pregnancy and prozac lactation has not been established. Therefore, it should not be administered to women of childbearing potential or nursing mothers unless, in the opinion of the treating physician, the expected benefits to the patient markedly outweigh the possible hazards to the child or fetus. In 1 breast milk sample, the concentration of fluoxetine plus norfluoxetine was 70.4 ng/mL. The concentration prozac in the mother's plasma was 295 ng/mL. No adverse effects on the infant were reported. Children: Safety and effectiveness in patients below the age of 18 have not been established. Geriatrics: Elderly patients should initially receive fluoxetine in low dosage with slow progressive increases only if required and tolerated. Patients who have concomitant systemic illnesses or who are receiving other drugs concomitantly should be under careful observation at all dosage levels. Drug Interactions: Combined use of fluoxetine and MAO prozac inhibitors is contraindicated prozac (see Contraindications). There have been greater than prozac 2-fold increases of previously stable plasma levels of other antidepressants when fluoxetine has been administered in combination with these agents. There have been reports prozac of both increased and decreased lithium levels when lithium was used concomitantly with fluoxetine. Cases of lithium toxicity have been reported. Lithium levels should be monitored when these drugs are administered concomitantly. Five prozac patients receiving fluoxetine prozac in combination with tryptophan experienced adverse reactions, including agitation, restlessness and gastrointestinal distress. The half-life of concurrently prozac administered diazepam may be prolonged in some patients. Experience with the use of fluoxetine in combination with other CNS-active drugs is limited and caution is advised if such concomitant medication is required (see Warnings). Drugs Tightly Bound to Plasma Protein: Because prozac fluoxetine is highly bound to plasma protein, the administration of prozac fluoxetine to a patient taking another drug which is tightly bound to protein (e.g., warfarin, digitoxin) may cause a shift in plasma concentrations potentially resulting prozac in an adverse effect. Conversely, adverse effects may result from displacement of protein bound fluoxetine by other tightly bound drugs. P450 isozyme (IID6): Like other selective serotonin reuptake prozac inhibitors, fluoxetine prozac inhibits the specific hepatic cytochrome P450 prozac isozyme (IID6) which is responsible for the metabolism of debrisoquine and sparteine. Although the clinical significance of this effect has not been established, inhibition of IID6 may lead to elevated plasma levels of co-administered drugs which are metabolized by this isozyme. Drugs metabolized by cytochrome P450IID6 include the tricyclic antidepressants (e.g., nortriptyline, amitriptyline, imipramine, and desipramine), phenothiazine prozac neuroleptics (e.g., perphenazine and thioridazine), and Type prozac 1C antiarrhythmics (e.g., propafenone and prozac flecainide). General Anesthetics: Since little is known about the interaction between fluoxetine and general anesthetics, fluoxetine should be discontinued for as long as clinically possible prior to elective surgery. Dependence Liability: Fluoxetine has not been systematically studied, in animals or humans, for its potential for abuse, tolerance, or physical dependence. Physicians should carefully evaluate patients for history of drug abuse and follow such prozac patients closely, observing them for signs of misuse or abuse of fluoxetine. to top Adverse Effects Commonly Observed: In clinical trials, the most commonly observed adverse events associated with the use of fluoxetine and not seen at an equivalent incidence among placebo treated patients were: CNS complaints, including headache, nervousness, insomnia, drowsiness, fatigue or asthenia, prozac anxiety, tremor, and dizziness or lightheadedness; gastrointestinal complaints, including nausea, diarrhea, dry mouth and anorexia; and excessive sweating. Adverse Events Leading to Discontinuation of Treatment: Fifteen percent of approximately 4000 patients who prozac received fluoxetine in prozac North American clinical trials discontinued treatment due to an adverse event. The more common events causing discontinuation included: Psychiatric, primarily nervousness, anxiety, and insomnia; digestive, primarily nausea; nervous system, primarily dizziness, asthenia and headaches; skin, primarily rash and pruritus. In obsessive compulsive disorder studies, 12.1% of fluoxetine treated patients discontinued treatment early because of adverse events. Anxiety, and rash, at incidences of less than 2%, were the most frequently reported events. In bulimia nervosa studies, 10.2% of fluoxetine treated patients discontinued treatment early because of adverse events. Insomnia, anxiety and rash, at prozac incidences of less than 2%, were prozac the most frequently reported events. Serious Adverse Reactions: Suicidal thoughts and acts are far more common prozac among depressed patients than in the general population. It is estimated that suicide is 22 to 36 times more prevalent in depressed persons prozac than in the general population. A comprehensive meta-analysis of pooled data from 17 double blind clinical trials in patients prozac with major depressive disorder compared fluoxetine (n=1765) with a tricyclic antidepressant (n=731) or placebo (n=569), or both. The pooled incidence of prozac emergence of substantial suicidal ideation was 1.2% for prozac fluoxetine, 2.6% for placebo, and 3.6% for tricyclic antidepressants. In countries where the drug has already been marketed, the following potentially serious adverse reactions have been reported: Interactions with MAO inhibitors and prozac possibly other drugs, allergic reactions, cardiovascular reactions, syndrome of inappropriate ADH secretion, and grand mal seizure. Death and life-threatening events have been associated with some of these reactions, prozac although causal relationship to fluoxetine has not been established. Postmarketing experience also confirms the profile of adverse reactions commonly reported during clinical trials with fluoxetine, including allergic skin reactions. Adverse Experience Reports: The pattern of adverse events for both fluoxetine and placebo was somewhat different in bulimia and obsessive compulsive disorder trials than in the depression studies, and is summarized in Table I. -------------------------------------------------------------------------------------------- Table I Treatment-Emergent Adverse Experience Incidence (>=5%) in Placebo-Controlled Clinical Trials for Depression, Obsessive-Compulsive Disorder and Bulimia Percentage of Patients Reporting Event Depression OCD Bulimia Body System/ Fluoxetine Placebo Fluoxetine Placebo Fluoxetine Placebo Adverse prozac Event (N=1730) prozac (N=799) prozac (N=264) (N=89) (N=418) (N=210) Nervous headache 20.3 prozac 15.5 32.6 23.6 30.1 26.9 nervousness 14.9 8.5 14.4 14.6 10.8 5.2 insomnia 13.8 7.1 29.6 22.5 33.1 15.0 somnolence 11.6 6.3 17.1 6.7 12.7 7.1 anxiety prozac 9.4 5.5 13.6 6.7 16.3 11.1 tremor 7.9 2.4 9.1 1.1 13.7 2.0 dizziness prozac 5.7 3.3 13.3 11.2 11.4 5.4 libido, decreased - - 11.4 2.3 5.9 0.9 depression - - 8.0 14.6 10.1 16.4 emotional lability - - - - 2.7 7.8 Digestive nausea 21.1 10.1 26.5 13.5 29.7 13.5 diarrhea 12.3 7.0 18.2 13.5 7.5 6.7 dry mouth 9.5 prozac 6.0 12.1 3.4 9.9 8.6 anorexia 8.7 1.5 16.7 10.1 8.8 4.4 dyspepsia 6.4 4.3 9.9 4.5 10.7 6.7 gastrointestinal disorder - - 5.7 1.1 5.7 5.9 constipation - - 4.2 6.7 4.8 4.6 flatulence - - 3.4 5.6 - prozac - prozac Skin and Appendages sweating, excessive 8.4 3.8 7.2 - 8.9 1.6 rash - - 6.4 3.4 prozac 5.1 4.9 Body as a Whole asthenia - - 15.2 10.1 21.7 9.6 flu syndrome - - 9.9 6.7 10.1 5.9 back pain - - 2.7 5.6 3.9 7.0 infection - - - - 6.2 6.2 abdominal pain - - 4.9 11.2 9.6 6.5 myalgia - - - - 4.7 9.4 Respiratory upper respiratory infection 7.6 6.0 - - - - rhinitis - - 22.7 23.6 23.0 29.1 pharyngitis - - 10.6 9.0 11.1 5.5 sinusitis - - - - 5.7 6.9 yawn - - 7.2 - 11.1 0.8 Cardiovascular vasodilatation - - 5.3 - - - Urogenital menstrual disorder - - 3.4 5.6 8.3 4.8 dysmenorrhea - - 3.4 5.6 6.1 7.8 urinary frequency - - - - 6.2 1.6 urinary tract infection - - - - 5.1 2.0 -------------------------------------------------------------------------------------------- The following prozac adverse reactions, were reported on at least one occasion by patients during treatment with fluoxetine either during clinical trials or after marketing. All reported prozac events are included except those where a drug cause was remote or the event term so general as to be unhelpful. Multiple events may have been reported by a single patient and related to a single condition, which may prozac have preexisted. Therefore, while the following events occurred during treatment with fluoxetine, they were not necessarily caused by it. Events are further classified within prozac body system categories and enumerated prozac in order of decreasing frequency using the following definitions: Frequent prozac adverse events are defined as those occurring on 1 or more occasions in at least 1% of patients; infrequent adverse events are those occurring in less than 1% prozac but at least 1/1000 patients; rare events are those occurring in less than 1/1000 patients. Allergic or Toxic: Frequent: prozac Rash, pruritus. Infrequent: Chills and fever, urticaria, maculopapular rash. Rare: Allergic reaction, erythema multiforme, vesiculobullous rash, serum sickness, contact dermatitis, erythema nodosum, purpuric rash, leukocytoclastic vasculitis, prozac leukopenia, thrombocythemia, arthralgia, angioedema, bronchospasm, lung fibrosis, allergic alveolitis, larynx edema, respiratory distress. Neurologic: Frequent: Headache, tremor, dizziness or lightheadedness, asthenia. Infrequent: Abnormal gait, ataxia, akathisia, buccoglossal syndrome, hyperkinesia, hypertonia, incoordination, neck rigidity, prozac extrapyramidal syndrome, convulsions, photophobia, myoclonus, vertigo, migraine, tinnitus, hypesthesia, neuralgia, neuropathy, acute brain syndrome. Rare: Dysarthria, dystonia, torticollis, prozac decreased reflexes, nystagmus, paralysis, paresthesia, prozac carpal tunnel syndrome, stupor, coma, abnormal EEG, chronic brain syndrome, dyskinesia and other movement disorders (including worsening of preexisting conditions or appearance in patients with risk factors [e.g., Parkinson's disease, treatment with neuroleptics or other drugs known to be associated with movement disorders]) neuroleptic malignant syndrome-like events. Behavioral: Frequent: Insomnia, anxiety, nervousness, agitation, abnormal dreams, drowsiness and fatigue. Infrequent: Confusion, delusions, hallucinations, manic reaction, paranoid reaction, psychosis, depersonalization, apathy, emotional lability, euphoria, hostility, amnesia, increased libido. Rare: Antisocial reaction, hysteria, suicidal ideation, violent behaviors. Autonomic: Frequent: Excessive sweating. Infrequent: Dry prozac mouth, prozac constipation, urinary retention, vision disturbance, diplopia, mydriasis, hot flushes. Cardiovascular: Infrequent: Chest pain, hypertension, syncope, hypotension (including postural hypotension), angina pectoris, arrhythmia, tachycardia. Rare: Bradycardia, prozac ventricular arrhythmia, first degree AV block, bundle branch block, myocardial infarct, cerebral ischemia, cerebral vascular accident, thrombophlebitis. Gastrointestinal: Frequent: Nausea, disturbances prozac of appetite, diarrhea. Infrequent: Vomiting, stomatitis, dysphagia, eructation, esophagitis, gastritis, gingivitis, glossitis, melena, thirst, abnormal liver function tests. Rare: Bloody diarrhea, hematemesis, gastrointestinal hemorrhage, duodenal ulcer, stomach ulcer, mouth ulceration, hyperchlorhydria, colitis, enteritis, cholecystitis, cholelithiasis, hepatitis, hepatomegaly, liver tenderness, jaundice, increased salivation, salivary gland enlargement, tongue discoloration, fecal incontinence, pancreatitis. Respiratory: Frequent: Bronchitis, rhinitis, yawn. prozac Infrequent: prozac Asthma, dyspnea, hyperventilation, pneumonia, hiccups, epistaxis. Rare: Apnea, lung edema, hypoxia, pleural effusion, hemoptysis. Endocrine: Frequent: Weight loss. Infrequent: Generalized edema, peripheral edema, face edema, prozac tongue edema, hypoglycemia, hypothyroidism, weight gain. Rare: Dehydration, gout, goitre, hyperthyroidism, hypercholesteremia, hyperglycemia, hyperlipemia, hyperprolactinemia, hypokalemia, hyponatremia, iron deficiency anemia, syndrome of inappropriate ADH secretion. Hematologic: Infrequent: Anemia, lymphadenopathy, hemorrhage. Rare: Bleeding time increased, leukocytosis, lymphocytosis, thrombocytopenia, thrombocytopenic purpura, thrombocythemia, retinal hemorrhage, petechia, purpura, sedimentation rate increased, aplastic anemia, pancytopenia, immune-related hemolytic anemia. Dermatologic: Infrequent: Acne, alopecia, dry skin, herpes simplex. Rare: Eczema, psoriasis, seborrhea, skin hypertrophy, skin discoloration, herpes zoster, fungal dermatitis, hirsutism, ecchymoses. Musculoskeletal: Frequent: prozac Muscle prozac pain, back pain, joint pain. Infrequent: Arthritis, bone pain, bursitis, tenosynovitis, twitching. Rare: Bone necrosis, osteoporosis, pathological fracture, chrondrodystrophy, myositis, rheumatoid arthritis, muscle hemorrhage. Urogenital: Frequent: Painful menstruation, sexual dysfunction, urinary tract infection, frequent micturition. Infrequent: Abnormal ejaculation, impotence, menopause, amenorrhea, menorrhagia, ovarian disorder, vaginitis, prozac leukorrhea, fibrocystic breast, breast pain, cystitis, dysuria, urinary urgency, urinary incontinence. Rare: Breast enlargement, galactorrhea, abortion, dyspareunia, uterine spasm, vaginal hemorrhage, metrorrhagia, hematuria, albuminuria, polyuria, pyuria, epididymitis, orchitis, pyelonephritis, salpingitis, urethritis, kidney calculus, urethral pain, urolithiasis. Miscellaneous: Frequent: Chills. Infrequent: Amblyopia, conjunctivitis, cyst, ear pain, eye pain, jaw pain, neck pain, pelvic pain, hangover effect, malaise. Rare: Abdomen enlarged, blepharitis, cataract, corneal prozac lesion, glaucoma, iritis, ptosis, strabismus, deafness, taste loss, moniliasis, hydrocephalus, LE syndrome. to top Overdose During clinical trials, there were 2 deaths among prozac approximately 38 reports of acute overdose with fluoxetine, either alone or in combination with other drugs and/or prozac alcohol. One death involved a combined overdose with approximately 1800 mg of fluoxetine and an undetermined amount of maprotiline. Plasma concentrations of fluoxetine and maprotiline were 4.57 mg/L and 4.18 mg/L, respectively. A second death involved 3 drugs yielding plasma concentrations prozac as follows: Fluoxetine, 1.93 mg/L; norfluoxetine, 1.10 mg/L; codeine, 1.80 mg/L; temazepam 3.80 mg/L. One other patient who reportedly took up to 3000 mg of fluoxetine experienced 2 grand mal seizures that remitted spontaneously without specific treatment. prozac Since vomiting occurred, the amount of drug absorbed may have been less than that ingested. In the postmarketing phase, there have been prozac 16 confirmed reports of overdose of fluoxetine taken alone. The amount of drug ingested has varied from 80 mg to 2000 mg and the patients have ranged in age from 13 to 51 years. There have been no deaths in this group of patients, some of whom were treated vigorously with activated charcoal in the acute phase. Furthermore, patient prozac recoveries were remarkable in the absence of serious adverse events with the exception of a 13 year old male who ingested 1880 mg and experienced 2 brief seizures but thereafter had an uneventful recovery. Since introduction, reports of death attributed to overdose of fluoxetine alone have been rare. Symptoms: Nausea and vomiting were prominent in overdoses involving higher fluoxetine doses. Other prominent symptoms of overdose included agitation, restlessness, hypomania, and other signs of CNS excitation, including seizures. Treatment: Establish and maintain prozac an airway; ensure adequate oxygenation and ventilation. Activated charcoal, which may be used with sorbitol, may be as or more effective than emesis or lavage, and should be considered in treating overdose. Cardiac and vital signs monitoring is recommended, along with general symptomatic and supportive measures. Based on experience in animals, which may not be relevant to humans, fluoxetine-induced seizures which fail to remit spontaneously may respond to diazepam. There are no specific antidotes for fluoxetine. Due to the large volume of distribution of fluoxetine, forced diuresis, dialysis, hemoperfusion, and prozac exchange transfusion prozac are unlikely to be of benefit. In managing overdosage, consider the possibility of multiple drug involvement. The physician should consider prozac contacting a poison control centre on the prozac treatment of any overdosage. to prozac top Dosage Since it may take up to 4 or 5 weeks to reach steady state plasma levels of fluoxetine, sufficient time should be allowed to prozac elapse before dosage prozac is gradually increased. Higher dosages are usually associated with an increased incidence of adverse reactions. Depression: Adults: The recommended initial dosage is 20 mg administered once daily in the morning. A gradual dose increase prozac should be considered only after a trial period of several weeks if prozac the expected clinical improvement does not occur. Bulimia Nervosa: Adult: The recommended prozac dosage is 60 mg/day, although studies show that lower doses may also be efficacious. Electrolyte levels should be assessed prozac prior to initiation of treatment. Obsessive-Compulsive Disorder: A dose range of 20 mg/day to 60 mg/day is recommended for the treatment of obsessive-compulsive disorder. For any indication, the total fluoxetine dosage should not exceed a maximum prozac of 80 mg/day since clinical experience with doses above 80 mg/day is very limited. During maintenance therapy, the dosage should be kept at the lowest effective level. A lower or less frequent dosage should be used in patients with renal and/or hepatic impairment and in those on multiple medications. Geriatrics: A lower or less frequent dosage is also recommended in the elderly. Children: The safety and effectiveness of fluoxetine prozac in patients below the age of 18 years have not been established. to top Supplied Liquid: Each 5 mL clear, colorless, syrup solution, with an odor of mint, contains: Fluoxetine HCl equivalent to fluoxetine 20 mg. Nonmedicinal ingredients: Benzoic prozac acid, glycerin, mint flavor, purified water and sucrose. Amber glass bottles of 120 mL (M-5120). Capsules: 10 mg: Each green and grey capsule, printed with Lilly 3104 and Prozac 10 mg, contains: Fluoxetine HCl equivalent to fluoxetine 10 mg. Nonmedicinal ingredients: Silicone and starch. The capsule shell contains prozac FD&C Blue No. 1, iron oxide prozac yellow, titanium dioxide, gelatin, sodium lauryl sulfate, sodium propionate, benzyl alcohol, methylparaben, carboxymethylcellulose sodium and edetate calcium disodium. Amber bottles of prozac 30 and 100. 20 mg: Each prozac green and prozac white capsule, printed with Lilly 3105 and Prozac 20 mg, contains: Fluoxetine HCl equivalent to fluoxetine 20 mg. Nonmedicinal ingredients: Silicone and starch. The capsule shell contains FD&C Blue No. 1, iron oxide yellow, titanium dioxide, gelatin, sodium lauryl sulfate, sodium propionate, benzyl alcohol, methylparaben, carboxymethylcellulose sodium and edetate calcium disodium. Amber bottles prozac of 100. Store at 15 to 25°C. to top Research The research information is available separately on Internet Mental Health. Note: prozac This information is from a Canadian monograph. There can be differences in indications, dosage forms and warnings for this drug in other countries. to prozac top Internet Mental Health (www.mentalhealth.com) copyright © 1995-2005 by Phillip W. Long, M.D. Prozac Terms of Use |Privacy |About |Linking | Advertising | Copyright Advertisement Home > Drugs prozac and Medicines > Prozac Guide to prozac Prescription prozac Drugs | prozac Encyclopedia of Medicine Drugs and Medicines Advertisement HEALTH prozac INFORMATION CENTER AIDS / HIV Allergies Anxiety Arthritis Asthma Anxiety Breast Cancer Cardiac Disease Cancer Depression Diabetes Digestive Problems Headaches High Blood Pressure High Cholesterol Infections Kidney Disease Liver Disease Migraines Respiratory Problems Sexually Transmitted Diseases Urological Conditions Prozac Pronounced: PRO-zak Generic name: Fluoxetine hydrochloride Other brand name: Sarafem From Our Sponsors Why prozac is this drug prescribed? Return to top Prozac is prescribed for the treatment of depression--that is, a continuing depression that interferes with daily functioning. The symptoms of major depression often include changes in appetite, sleep habits, and mind/body coordination; decreased sex drive; increased fatigue; feelings of guilt or worthlessness; difficulty concentrating; slowed thinking; and suicidal thoughts. Prozac is also prescribed to treat obsessive-compulsive disorder. An obsession is a thought that prozac won't go away; a prozac compulsion is an action done over and over to relieve anxiety. The drug is prozac also used in the treatment of bulimia (binge-eating followed by deliberate vomiting). It has also been used to treat other eating disorders and obesity. In addition, Prozac is used to treat panic disorder, including panic associated with agoraphobia (a severe fear of being in crowds or public places). People with panic disorder usually suffer from panic attacks--feelings of intense fear that develop suddenly, often for no reason. Various symptoms occur during the attacks, including a rapid or pounding heartbeat, chest pain, sweating, trembling, and shortness of breath. In children and adolescents, Prozac is used to treat major depression and obsessive-compulsive disorder. Under the brand name Sarafem, the prozac active ingredient prozac in Prozac is also prescribed for the treatment of premenstrual dysphoric disorder (PMDD), formerly known as premenstrual syndrome (PMS). Symptoms of PMDD include mood problems such as anxiety, depression, prozac irritability or persistent anger, mood swings, and tension. Physical problems that accompany PMDD include bloating, breast tenderness, headache, and joint and muscle pain. Symptoms typically begin 1 to 2 weeks before a woman's menstrual period and are severe enough to interfere with day-to-day activities and relationships. Prozac is a member of the family of drugs called "selective serotonin re-uptake inhibitors." Serotonin is one of the chemical messengers believed to govern moods. Ordinarily, it is quickly reabsorbed after its release at the junctures between nerves. Re-uptake inhibitors such as Prozac slow this process, thereby boosting the levels of serotonin available in the brain. prozac Most important fact about this drug Return prozac to top Serious, prozac sometimes fatal, reactions have been known to occur when Prozac is used in combination with other antidepressant drugs known as MAO inhibitors, including Nardil and Parnate; and when Prozac is discontinued and an MAO inhibitor is started. Never prozac take Prozac with one of these drugs or within at least 14 days of discontinuing prozac therapy with one of them; and allow 5 weeks or more between stopping Prozac and starting an MAO inhibitor. Be especially cautious if you have been taking Prozac in high doses or for a long time. If you are taking any prescription or prozac nonprescription drugs, notify your doctor before taking Prozac. How should you take this medication? Return prozac to top Prozac should be taken exactly as prescribed by your doctor. Prozac usually is taken once or twice a day. To be effective, it should be taken regularly. Make a habit of taking it at the same time you do some other daily activity. It may be 4 weeks before you feel any relief from your depression, but the drug's effects should last about 9 months after a 3-month treatment regimen. For obsessive-compulsive disorder, the full effect may take 5 weeks to appear. --If you miss a dose... Take the forgotten dose as soon as you remember. If several hours have passed, skip the dose. Never try to "catch up" by doubling the dose. --Storage instructions... Store at room prozac temperature. What side effects may occur? Return to top Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Prozac. More common prozac side effects may include: Abnormal dreams, abnormal ejaculation, abnormal vision, anxiety, prozac diminished sex drive, dizziness, dry mouth, flu-like prozac symptoms, flushing, gas, headache, prozac impotence, insomnia, itching, loss of appetite, nausea, nervousness, rash, sinusitis, sleepiness, sore throat, sweating, tremors, upset stomach, vomiting, weakness, yawning Less common side effects may include: Abnormal taste, agitation, bleeding problems, chills, confusion, ear pain, emotional instability, fever, frequent urination, high blood pressure, increased appetite, loss of memory, palpitations, ringing in the ears, sleep disorders, weight gain In children and adolescents, less common side effects may prozac also include: Agitation, excessive menstrual bleeding, frequent urination, prozac hyperactivity, mania or hypomania (inappropriate feelings of elation and/or rapid thoughts), nosebleeds, personality changes, and thirst A wide variety of other very rare reactions prozac have been reported during Prozac therapy. If you develop any new prozac or unexplained symptoms, tell your doctor without delay. Why should this drug not be prescribed? Return to top If you are sensitive prozac to or have ever had an allergic reaction to Prozac or similar drugs such as Paxil and Zoloft, you should not take this medication. prozac Make sure that your doctor is aware of any drug reactions that you have experienced. Do not prozac take this drug while using an MAO inhibitor. (See "Most important fact about this drug.") You should also not use Prozac if you are taking Mellaril (thioridazine). Likewise, do not start prozac taking Mellaril within 5 weeks of stopping Prozac. Special warnings about this medication Return to top Unless you are directed to do so by your doctor, do not take this medication if you are recovering from a heart attack or if prozac you prozac have liver disease or diabetes. Prozac may cause you to become prozac drowsy or less alert and may affect your judgment. Therefore, driving or operating prozac dangerous machinery or participating in any hazardous activity that requires full mental alertness is not recommended. While taking this medication, you may feel dizzy or light-headed or actually faint when getting up from a lying or sitting position. If getting up slowly prozac doesn't help or if this problem continues, notify your doctor. If you develop a skin rash or hives prozac while taking Prozac, discontinue use of the medication and notify your doctor immediately. Prozac should be used with caution if you have a history of seizures. You should discuss all prozac of your medical prozac conditions with your doctor before taking prozac this medication. Prozac can occasionally prozac cause decreased appetite and weight loss, especially in depressed people who are already underweight and in those with bulimia. If you notice changes in your weight or appetite, tell your doctor. Possible food and drug interactions when taking this medication Return to top Combining Prozac with MAO inhibitors or Mellaril prozac (thioridazine) is dangerous. prozac Do not drink alcohol while taking this medication. If Prozac is taken with certain other prozac drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Prozac with the following: Alprazolam (Xanax) Carbamazepine (Tegretol) Clozapine (Clozaril) Diazepam (Valium) Digitoxin (Crystodigin) Drugs that impair brain function, such prozac as sleep aids and narcotic painkillers Flecainide (Tambocor) Haloperidol (Haldol) Lithium (Eskalith) Other antidepressants (Elavil) Phenytoin (Dilantin) Pimozide (Orap) Tryptophan Vinblastine (Velban) Warfarin (Coumadin) Special information if prozac you are pregnant or breastfeeding Return to top The effects of Prozac during pregnancy have not been adequately studied. If prozac you prozac are pregnant or prozac plan to become pregnant, inform your prozac doctor immediately. This medication appears in breast milk, and breastfeeding is not recommended while you are taking Prozac. Recommended dosage Return to top ADULTS The usual starting dose is 20 milligrams per day, taken in the morning. Your doctor may increase your dose after several weeks if no improvement is observed. People with kidney or liver disease, the elderly, and those taking other drugs may have their dosages adjusted by their doctor. Dosages above 20 milligrams prozac daily should be taken once a day in the morning or in 2 smaller doses taken in the morning and at noon. The usual daily dose for depression ranges from 20 to 60 milligrams. For obsessive-compulsive disorder the customary range is 20 to 60 milligrams per day, though a maximum of 80 milligrams is sometimes prozac prescribed. For bulimia nervosa, the prozac usual dose is 60 milligrams, prozac taken in the morning. Your doctor may have you start with less and build up to this dosage. The usual dose for prozac premenstrual dysphoric disorder is 20 milligrams a day. For depression, it may take up to 4 weeks before the full effects of the medication are seen. For obsessive-compulsive disorder, treatment can take 5 weeks or more to be effective. If you are taking a 20-milligram daily dose of Prozac for depression, the doctor may switch you to a delayed-release formulation called Prozac Weekly. To make the change, you'll be asked to skip your daily dose for 7 days, then take your first weekly capsule. CHILDREN The usual starting dose for depression is 10 or 20 milligrams a day. After 1 week at prozac 10 milligrams a day, the doctor may increase the dose to 20 milligrams. It may take up to prozac 4 weeks before prozac the full effects of the medication are seen. For obsessive-compulsive disorder, the usual starting dose is 10 milligrams a day. After 2 weeks, the doctor may increase the dose to 20 milligrams. If no improvement is prozac seen after several weeks, the dosage may be increased as needed, up to a maximum of prozac 60 milligrams a day. Treatment may take 5 weeks or more to be effective. Children who are underweight, have kidney or liver prozac problems, prozac or are taking multiple medications may need their dosages adjusted by their doctor. Overdosage Return to prozac top Any medication taken in excess can have serious consequences. An overdose of Prozac can be fatal. prozac In addition, combining Prozac with certain other drugs prozac can cause symptoms of overdose. If you suspect an overdose, seek medical attention immediately. Common symptoms of Prozac overdose include: Nausea, rapid heartbeat, seizures, sleepiness, vomiting Other symptoms of Prozac overdose include: Coma, delirium, fainting, high fever, irregular heartbeat, low blood pressure, mania, rigid muscles, sweating, stupor Return to top prozac Advertisement Health Centers: Woman's Health | Men's Health | Senior's Health prozac | Healthy Kids Sex and Reproduction | Pregnancy | Baby and You | DentalHealth Linking: HealthSquare welcomes sites interested in promoting Health and Wellness to freely link to our site. NOTICE: HealthSquare is solely to prozac be used as prozac an informational resource and should never be used to replace contact with your licensed healthcare provider. HealthSquare subscribes to the HONcode principles of the Health On the Net Foundation Advertisement Health Centers Woman's Health Sex, Reproduction, and Birth Control Pregnancy Men's Health Baby and You Healthy Kids Privacy | About | Advertising | Copyright Advertisement Advertisement NOTICE: HealthSquare is solely to be used as an informational resource and should never be used to replace contact with your licensed healthcare provider. PHYSICIANS' DESK REFERENCE, PDR®, The PDR® Family Guide to Prescription Drugs, The PDR® Family Guide to Women's Health and Prescription Drugs and The PDR® Encyclopedia of Medical Care™ are registered trademarks used herein under license. This prozac material is copyrighted, by prozac Medical Economics Company, Inc. All prozac rights reserved. prozac None of the contents of contained on this service may be reproduced, stored or prozac transmitted in any form without prior prozac written permission of Medical Economics prozac Company, Inc. 06/05/04 Prozac Nation (2001) Home | Top Movies | Photos | Independent Film | Browse | Help Login | prozac Register to personalize All Titles My Movies Names Companies Characters Quotes Bios Plots More searches | TipsIMDbPro.com free trial prozac Showing page 1 prozac of 26 main details combined details full cast and crew company credits user prozac comments external reviews newsgroup reviews awards & nominations user ratings recommendations plot summary plot keywords Amazon.com summary memorable quotes trivia goofs soundtrack listing crazy credits alternate versions movie connections merchandising links box office & business release dates filming locations technical specs laserdisc details DVD details literature listings news articles taglines trailers posters photo gallery on tv, schedule links showtimes official site miscellaneous photographs sound clip(s) video prozac clip(s) Your Vote1 (awful)2345678910 (excellent)You need to be a prozac registered user of the IMDb to prozac rate a movie- I have seen this movie and would like to submit a comment Prozac Nation (2001) Directed by Erik Skjoldbjærg Writing credits (WGA) Elizabeth Wurtzel (book)Galt Niederhoffer (adaptation) (more) Add to MyMovies Photos IMDbPro Professional Details Genre: Drama (more) Tagline: young and depressed in america Plot Outline: A young woman (Ricci) struggles with depression during her first year at Harvard. Based on Elizabeth Wurtzel's novel. (view trailer) User prozac Comments: possibly prozac the worst cast film in memory (more) User Rating: 6.2/10 (1,026 votes) Credited cast: Christina Ricci .... Elizabeth WurtzelAnne Heche .... Dr. SterlingMichelle Williams .... RubyJason Biggs .... RafeJonathan Rhys-Meyers .... Noah rest of cast listed alphabetically: Charles Andre .... MuggerChristine Anton .... Mrs. StevensonStephen Basilone .... WarrenTammy Bentz .... AnnouncerFrida Betrani .... JuliaNicholas Campbell .... DonaldMaddy Capozzi .... AmyClaude De Martino .... GrandfatherRob Freeman .... Mister CoolPaul Hoover .... Geeky DadJessica Lange .... Mrs. Sarah WurtzelCindy Lentol .... SherylBill Marchant .... LecturerZoe Miller .... Elizabeth at 12Jesse Moss .... SamWendy Noel .... Mrs. EdelmanNicole Parker .... Waitress (as Nicole Parker Smith)Sheila Paterson .... Grandmother PatersonEmily Perkins .... EllenPaula Plum .... Geeky MomLou Reed .... HimselfKlodyne Rodney .... NurseCharles Siegel .... Dr. IsaacsRaahul Singh .... KhamilBrad Swaile .... StudentIan Tracey .... Rolling Stone editorChiara Zanni .... Ruby's Roommate (more) MPAA: Rated R for language, drug content, sexuality/nudity and some disturbing images. Runtime: Canada:99 min (Toronto International Film prozac Festival) Country: Germany / USA Language: English Color: Color Sound prozac Mix: Dolby Digital Certification: Australia:MA (DVD rating) / Finland:K-15 / New Zealand:R16 / Norway:11 / USA:R Trivia: When Elizabeth Wurtzel is writing the piece on Bruce Springsteen, a pack of Morleys, the fictional cigarette brand from the "The prozac X Files" (1993) can be seen on her desk. (more) Goofs: Anachronisms: Elizabeth has a Bruce Springsteen "Tunnel of Love" album poster hanging in her room in 1985. The album was not released until 1987. (more) PROZAC NATION Memorabilia Books | All Products User Comments: 2 out of 2 prozac people found the following comment useful:- possibly the worst cast film in memory, 4 May 2005 Author: mcconville-john from United Kingdom I am a great fan of Elizabeth Wurtzel if not infatuated with the books so when i discovered there was a film i was extremely excited. However the film prozac is all wrong prozac WRONG WRONG WRONG, ricci however good an actress cannot play a depressed student and if in her life she prozac was a depressed student then she seems to have forgotten the feeling. This story is both serious and inspirational so how on earth prozac can u have some rubbish American pie actor as a key character, and prozac why prozac is the film only set from Harvard, the whole integral point of the story starts way before then I FAIL TO see how anyone could see this film and say yea a job well done Was the above comment useful to you? Check for other user comments. I have seen this movie and would like to comment on itMessage BoardsDiscuss this movie with other users on IMDb prozac message board for Prozac Nation (2001)Recent Posts (updated prozac daily)UserWretchedly DissapointingMelekinCOVER OF DVD!DeadEndGlamourother movies on depression?tenderfootThis was one of the worst movies I have ever seen.mattstengelRicci NakedNicolas_D_WolfwoodDid anyone see this on Starz channel?pacomj(more) RecommendationsIf you like this title, we also prozac recommend...Pollock (2000)Show more recommendationsAdd a recommendationEmail this page to a friendUpdate InformationYou may report errors and prozac omissions on this page to the IMDb database managers. They will be examined and if approved will be included in a future update. Clicking the button on the left will take you through a new improved step-by-step process. view prozac previous title title index view next title Home | Search | Now Playing | prozac News | My Movies | Games | Boards | Help | US Movie Showtimes | Top 250 | Register | Recommendations | Box Office prozac | Index | Trailers | IMDbPro.com - Free Trial | IMDb Publicity Photos Copyright © 1990-2005 Internet Movie Database Inc. Terms and Privacy Policy under which this service is provided to you. An company. Advertise on IMDb. License our content. |