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| horse it lasix use why lasix for dog salem lasix bend lasix lasix eye surgery maryland correction lasix virginia vision lasix phentermine cramp lasix leg taking while lasix washington lasix side effects eugene eye lasix surgery buy lasix online vancouver lasix eye surgery horse racing lasix lasix generic lasix sale lasix eye | lasix Lasix Special , Furosemide Return to Home Page Printer Friendly Version USP DI Vol. II - DIURETICS, LOOP (Systemic) DIURETICS, LOOP (Systemic) Some commonly used brand names are: In the U.S.— Bumex 1 Edecrin 2 Lasix 3 Myrosemide 3 In Canada— Apo-Furosemide 3 Edecrin 2 Furoside 3 Lasix 3 Lasix lasix special Special 3 Novosemide 3 Uritol 3 Note: For quick reference, the following loop diuretics are numbered to match lasix special the corresponding lasix special brand names. This information applies to the following medicines: 1. Bumetanide (byoo-MET-a-nide)†‡ 2. Ethacrynic Acid lasix special (eth-a-KRIN-ik AS-id) 3. Furosemide (fur-OH-se-mide)‡§ † Not commercially lasix special available in Canada ‡ Generic name product may be available lasix special in the U.S. § Generic name product may be lasix special available in Canada Category Antihypercalcemic—Bumetanide; Ethacrynic Acid; FurosemideAntihypertensive—Bumetanide; Ethacrynic Acid; FurosemideDiagnostic aid adjunct, renal disease—FurosemideDiuretic—Bumetanide; Ethacrynic Acid; Furosemide Description Loop diuretics are lasix special given lasix special to help reduce the amount of water in the body. They work by acting lasix special on the kidneys to increase the flow of urine. Furosemide is also used to treat high blood pressure (hypertension) in those patients who are not helped by other medicines or in those patients who have kidney problems. High blood pressure adds to the lasix special work load of the heart and arteries. If it continues for a long time, the heart lasix special and arteries may not function properly. This can damage lasix special the blood vessels lasix special of the brain, lasix special heart, and kidneys, resulting in a stroke, heart failure, or lasix special kidney failure. High blood pressure may also increase the risk of heart attacks. lasix special These problems may be less likely to occur if blood pressure is controlled. Loop diuretics may also be used for other conditions as determined by your doctor. This lasix special medicine is available only with your doctor's prescription, in the following dosage forms: Oral Bumetanide Tablets lasix special (U.S.) Ethacrynic Acid Oral solution (U.S. and lasix special Canada) Tablets (U.S. and Canada) Furosemide Oral solution (U.S. and Canada) Tablets (U.S. and Canada) Parenteral Bumetanide Injection (U.S.) Ethacrynic Acid Injection (U.S. and Canada) Furosemide Injection (U.S. and Canada) Before Using This Medicine In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your lasix special doctor will make. For loop diuretics, the following should be considered: Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to bumetanide, ethacrynic acid, furosemide, sulfonamides (sulfa drugs), or thiazide diuretics (water pills). Also tell your health care professional lasix special if you are allergic to any other substances, lasix special such as foods, preservatives, or dyes. Pregnancy—Studies have not been lasix special done in pregnant women. However, studies in animals have shown this medicine to cause harmful effects.In general, diuretics are not useful for normal swelling of feet and hands that occurs during pregnancy. Diuretics should not be taken during pregnancy unless recommended by your doctor. Breast-feeding—These medicines have not been reported lasix special to cause problems in nursing babies. Furosemide passes into breast milk; it is not known whether bumetanide or ethacrynic acid passes into breast milk. Children—Although there is no specific information comparing the use of loop diuretics in children with use in any other age group, these medicines are not lasix special expected to cause different side effects in children than they do in adults. Older adults—Dizziness, lightheadedness, lasix special or signs of lasix special too much potassium loss may be more likely to occur in the elderly, who are more sensitive to the effects lasix special of this medicine. Elderly patients may also be more likely to develop lasix special blood clots. Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor lasix special may want to change the dose, or other precautions may be necessary. When you are taking loop diuretics, it is especially important that your health care professional know if you are taking any other medicines. Other medical problems—The presence of other medical problems may affect the use lasix special of loop diuretics. lasix special Make sure you tell your doctor if you have any other medical problems, especially: Diabetes mellitus (sugar diabetes)—Loop diuretics may increase the amount of sugar in the blood Gout or Hearing problems or Pancreatitis (inflammation of the pancreas)—Loop diuretics may make these conditions worse Heart attack, recent—Use of lasix special loop diuretics after a recent heart attack may increase the chance of side effects Kidney disease (severe) or Liver disease—Higher blood levels of the loop diuretic may occur, which may increase the chance of side effects Lupus erythematosus (history of)—Ethacrynic acid and furosemide may make this condition worse Proper Use of This Medicine This medicine may lasix special cause lasix special you to have an unusual feeling lasix special of lasix special tiredness when you begin to take it. You may also notice an increase in the amount of urine or in your frequency of urination. After you have taken the medicine for a while, these effects should lessen. In general, to keep the increase in lasix special urine from affecting your sleep: If you are to take a single dose a lasix special day, take it in the morning after breakfast. If you are to take more than one dose a day, take the last dose lasix special no later than 6 p.m., unless otherwise directed by your doctor. However, it is best to plan your dose or doses according to a schedule that will least affect your personal activities and sleep. Ask your lasix special health care professional to help you plan the best time to lasix special take lasix special this medicine. To help you remember to take your medicine, try to get into the habit of taking it at the same time each day. For patients taking the lasix special oral liquid lasix special form of furosemide: This medicine is to be taken by mouth even if it comes in a dropper bottle. If this medicine does not come in a lasix special dropper bottle, use a specially marked measuring spoon or lasix special other device to measure each dose accurately, lasix special since the average household teaspoon may not hold the right amount of liquid. For patients taking this medicine for high blood pressure : In lasix special addition to the use of the medicine your lasix special doctor has prescribed, appropriate treatment for your high blood pressure may include weight control and care in the types of foods lasix special you eat, especially foods high in sodium. Your doctor will tell lasix special you which factors are most important for you. You should check with your doctor before changing your diet. Many patients lasix special who have high blood pressure will lasix special not notice any signs of the problem. In fact, many lasix special may feel normal. It is very important that lasix special you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. Remember that this medicine will not cure lasix special your high blood pressure but it does help control it. Therefore, you must continue lasix special to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine lasix special for the rest of your life . If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease. If this medicine upsets your stomach, it may be taken with meals or milk. If stomach upset (nausea, vomiting, or stomach pain) continues or gets worse, or if you lasix special suddenly get lasix special severe diarrhea, check with your doctor. Dosing—The dose of loop lasix special diuretics will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of lasix special loop diuretics. If your dose is different, do not change it unless your doctor tells you to do so.The number of tablets lasix special or teaspoonfuls of solution that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time lasix special you take the lasix special medicine depend on the medical problem for which you are taking loop diuretics . For bumetanide For lasix special oral dosage lasix special form (tablets): To lower the amount of water in the body: Adults—0.5 to 2 milligrams (mg) once a day. lasix special Your doctor may increase your dose if needed. Children—Dose must be lasix special determined by your doctor. For injection dosage form: To lower the amount of water in the body: Adults—0.5 to 1 lasix special mg lasix special injected into a muscle or a vein every two to three hours as needed. Children—Dose must be determined by your doctor. For ethacrynic acid For oral dosage form (oral solution lasix special or tablets): To lower the amount of water in the body: Adults—50 to 200 milligrams (mg) a day. This may be taken as a single dose or divided into smaller doses. Children—At lasix special first, 25 mg a day. Your doctor lasix special may increase your dose lasix special as lasix special needed. For injection dosage form: To lower the amount of water in the body: Adults—50 mg injected into a vein every two to six hours as needed. Children—Dose is based on body weight and lasix special must be determined by your doctor. The usual lasix special dose is 1 mg per kilogram (kg) (0.45 mg per pound) of body weight injected lasix special into a vein. For lasix special furosemide For oral dosage form lasix special (oral solution or tablets): To lower the amount of water in the body: Adults—At first, 20 to 80 milligrams (mg) once a day. Then, your doctor lasix special may lasix special increase your dose as needed. Your doctor may tell you to take a dose lasix special once a day, lasix special two or three times a day, or every other day. Children—Dose is based on lasix special body weight and must be determined by your doctor. The lasix special usual dose is 2 mg per kilogram lasix special (kg) (0.91 mg per pound) of body weight for one dose. Then, your doctor may increase your dose every six to eight hours as needed. For high blood pressure: Adults—40 mg two times a day. lasix special Your doctor may increase your dose. For injection dosage form: To lower the lasix special amount of water lasix special in the lasix special body: Adults—At first, lasix special 20 to 40 mg injected into a muscle or a lasix special vein for one dose. Then, lasix special your doctor may increase your dose every two hours as needed. lasix special Once the medicine is working, the dose is injected into a muscle or a vein one or two times a day. Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 1 mg per kg (0.45 mg per pound) of lasix special body weight injected into a muscle or a vein for one dose. Your doctor may increase your dose every two hours as needed. For very high blood pressure: Adults—40 to 200 mg injected into a vein. Missed dose—If you miss a dose of lasix special this medicine, take it as soon as possible. However, lasix special if lasix special it is almost time for your next dose, skip the missed dose and lasix special go back to your regular dosing schedule. Do not double doses. Storage—To store this medicine: Keep out of the reach of children. Store away from heat and direct light. Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down. Keep the oral liquid form of lasix special this medicine from freezing. Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children. Precautions While Using This Medicine It is important that your lasix special doctor check lasix special your progress at regular visits to make sure that lasix special this medicine is working properly. This medicine may cause a loss of potassium from your body : lasix special To lasix special help prevent this, your doctor may want you to: eat or drink foods that have a high potassium content (for example, orange lasix special or other citrus fruit juices), or take a potassium supplement, or take another medicine to help prevent the loss of the potassium in the first place. It is very lasix special important to lasix special follow these directions. Also, it is important not to change your diet on your own. lasix special This is more important if you are already on a special diet (as for lasix special diabetes), or if you are taking a potassium supplement or a medicine to reduce potassium loss. Extra lasix special potassium may not be necessary and, in some cases, too much potassium could be harmful. To prevent the loss of too much water and lasix special potassium, tell your doctor if you become sick, especially with severe or continuing nausea and vomiting or diarrhea. Before having any kind of surgery (including dental surgery) or emergency treatment, make lasix special sure the medical doctor lasix special or dentist in charge knows that you are taking lasix special this medicine. Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position . This is more likely to occur in the morning. Getting up slowly may lasix special help . When you get up from lying down, lasix special sit on the edge of the bed with your feet dangling for 1 or 2 minutes. Then stand up slowly. If the problem continues or gets worse, check with lasix special your doctor. The dizziness, lightheadedness, or fainting is also more lasix special likely to occur if you drink alcohol, stand for long periods of time, exercise, or lasix special if the weather is hot. While you are taking this medicine, be careful to limit the amount of alcohol you drink. Also, use extra care during exercise or hot weather or if you must stand for lasix special long periods of time . For diabetic patients : This medicine may affect blood sugar levels. While you are using this medicine, lasix special be especially careful in testing for sugar in your blood lasix special or urine. For patients taking this medicine for high blood pressure : Do not take other medicines unless they have been discussed with your doctor . This especially includes over-the-counter (nonprescription) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, since they may tend to increase your blood lasix special pressure. For patients taking furosemide : Furosemide may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause lasix special a skin rash, itching, redness or other discoloration of lasix special the skin, or a severe sunburn. When you begin taking this medicine: Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible. Wear protective clothing, including a hat. Also, wear sunglasses. Apply a lasix special sun block product that has a skin protection factor (SPF) of at least lasix special 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. lasix special If you have any questions about this, check with your health care professional. Apply a sun block lipstick that has an SPF of lasix special at least 15 to protect your lips. Do not use lasix special a sunlamp or tanning bed or booth. If you have a severe reaction from the sun, lasix special check lasix special with your doctor . Side Effects of This Medicine Along with its lasix special needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor as soon as possible if any of the following side effects lasix special occur: Rare Black, tarry stools; blood in lasix special urine or stools; lasix special cough or hoarseness; fever or chills; joint pain; lower back lasix special or side pain; painful or difficult urination; pinpoint red spots on lasix special skin; ringing or buzzing in ears or any loss lasix special of lasix special hearing—more common with ethacrynic acid; skin rash or hives; stomach pain (severe) with nausea and vomiting; unusual bleeding or bruising; yellow eyes or skin; yellow vision—for furosemide only Signs and symptoms of too much potassium loss Dryness of mouth; increased thirst; irregular heartbeat; lasix special mood or mental changes; muscle cramps or pain; nausea or vomiting; unusual tiredness or weakness; weak pulseOther side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome: More common Dizziness or lightheadedness when getting up from lasix special a lying or sitting position Less lasix special common or rare Blurred vision; chest pain—with bumetanide only; confusion—with ethacrynic acid only; diarrhea—more common with ethacrynic acid; headache; increased sensitivity of skin to sunlight—with furosemide only; loss of appetite—more common with ethacrynic acid; nervousness—with ethacrynic lasix special acid only; premature ejaculation or difficulty in keeping an erection—with bumetanide only; redness or pain at place of injection; stomach cramps or painOther side effects not lasix special listed above may also occur in some patients. If you notice any other effects, lasix special check with your doctor. Additional Information Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, loop diuretics lasix special are lasix special used in lasix special certain patients with the following medical conditions: Hypercalcemia (too much calcium in the blood) Diagnostic aid for kidney disease Other than the above information, there is no additional information relating to proper use, precautions, or side effects lasix special for these uses. Revised: 08/02/94 Interim revision: 04/24/95 Copyright © 2000 Micromedex, Inc. All rights reserved. Licensed to Medical Strategies, Inc./Healthtouch®. USP DI® and Advice lasix special for the Patient® are registered trademarks of United States Pharmacopeial Convention (USP) used lasix special under license to Micromedex, Inc. Information is for End User's use only and may not be sold, redistributed or otherwise lasix special used for commercial purposes. The information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Additionally, the manufacture and distribution of herbal substances are lasix special not lasix special regulated in the United States, and no quality lasix special standards currently exist. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and lasix special effective for you. Please lasix special read the end user acknowledgement. http://www.healthtouch.com All pages Copyright© 1995-2005 by Cardinal ScriptNet RxMed: Pharmaceutical Information - lasix special LASIX SPECIAL LASIX® SPECIAL Hoechst Marion Roussel Furosemide Diuretic Action And Clinical Pharmacology: Animal experiments using stop-flow and micropuncture techniques lasix special have lasix special demonstrated that furosemide inhibits sodium reabsorption in the ascending limb of Henle's loop as well as in both proximal and distal tubules. lasix special The action of furosemide on the distal tubule is independent of any inhibitory effect on carbonic anhydrase or aldosterone. The diuretic effect of furosemide lasix special is exerted even when glomerular filtration is markedly impaired. lasix special Furosemide may promote diuresis in cases which have previously proved resistant to other diuretics. Furosemide lasix special has no significant pharmacological effects other than on renal function. Absorption, Metabolism and Excretion: lasix special In man, furosemide is rapidly absorbed from the gastrointestinal tract. The diuretic effect of furosemide is apparent within 1 hour following oral administration and the peak effect occurs in lasix special the first or second hour. The lasix special duration lasix special of action is 4 to 6 hours but may continue up to 8 hours. Following i.v. administration of the drug, the diuresis occurs within 30 minutes and the duration of action is about 2 hours. Urinary excretion is accomplished both by glomerular filtration and proximal tubular secretion, together this accounts for roughly only 2/3 of lasix special the ingested dose, the remainder being excreted in the feces. A small lasix special fraction is metabolized by cleavage of the side chain. Table I summarizes lasix special the lasix special elimination kinetics of furosemide in both normal subjects and patients with renal insufficiency. Indications And Clinical Uses: Lasix Special 500 mg tablets and 250 mg ampuls are high-dosage formulations of furosemide and are intended exclusively for patients with severely impaired renal function. They are to be used under strict medical lasix special supervision only lasix special within a hospital setting (see Dosage). High doses of furosemide may be used lasix special as an adjuvant treatment of lasix special oliguria and in the promotion of diuresis lasix special in the treatment of edema; in selected patients with acute renal lasix special failure, e.g., in the postoperative phase and in association with septic infections; in selected patients with chronic renal failure with fluid retention, both in the predialysis phase and when dialysis has become unavoidable, especially lasix special in the presence of acute pulmonary edema; in selected patients with lasix special the nephrotic syndrome with severe impairment of renal function, lasix special e.g., in chronic glomerular nephritis, lupus erythematosus and lasix special Kimmelstiel-Wilson syndrome. Contra-Indications: In patients with complete renal lasix special shutdown and glomerular filtration rate below 5 mL/minute. In patients whose glomerular filtration rate is above 20 mL/minute. lasix special In such cases, it might cause extremely lasix special severe water and electrolyte losses. lasix special Patients with hepatic cirrhosis, with renal failure due to poisoning with nephrotoxic or hepatotoxic substances and in patients with lasix special renal failure accompanied by hepatic coma and precoma. Severe hyponatremia, hypokalemia, hypovolemia lasix special or hypotension must be regarded as lasix special contraindications until serum electrolytes and fluid lasix special balance and blood pressure have been restored to normal lasix special levels. Known history of hypersensitivity to furosemide. Children: As furosemide may lasix special be capable of displacing bilirubin from albumin at least lasix special in vitro, it should not be administered lasix special to jaundiced newborn infants or to infants suffering from diseases (e.g., Rh incompatibility, familial non-hemolytic jaundice, etc.) with the potential of causing hyperbilirubinemia and possibly kernicterus. Manufacturers' Warnings In Clinical States: Furosemide is a potent diuretic which if given in excessive amounts can lead to a profound diuresis with water lasix special and lasix special electrolyte depletion. Therefore, careful medical supervision is required, and dose and dose schedule have to be adjusted to the individual patient's needs (see Dosage). Cases lasix special of tinnitus and reversible deafness have been reported. There have also been some reports of cases, the majority in children undergoing renal transplantation, in which permanent deafness has occurred. In these latter cases, the onset of deafness was usually insidious lasix special and gradually progressive up to lasix special 6 months after furosemide therapy. Hearing impairment is more likely to occur in patients with severely reduced renal function who are given large doses of furosemide parenterally, lasix special at a rate exceeding 4 mg/minute or in patients who are also lasix special receiving drugs known to be ototoxic. Sulfonamide diuretics have been reported lasix special to decrease arterial responsiveness to pressor amines and to lasix special enhance the effect of tubocurarine. Great caution should be exercised in administering curare or its lasix special derivatives to patients undergoing therapy with furosemide and it is advisable to discontinue furosemide for 1 lasix special week prior to any elective surgery. lasix special Pregnancy: The teratogenic lasix special and embryotoxic potential lasix special of furosemide in humans is unknown. The drug should not be used in pregnant women or in women of childbearing potential unless in lasix special the opinion of the attending physician the benefits to the patient outweigh the possible risk to the fetus. Lactation: It should be noted lasix special that lasix special diuretics may partially inhibit lactation and that furosemide passes into the breast milk. Precautions: General: During long-term therapy a lasix special high-potassium diet is recommended. Potassium supplements may be required especially when high doses are used for lasix special prolonged periods. Particular caution with potassium levels is necessary when the lasix special patient is on digitalis glycosides, potassium-depleting steroids, or in the case of infants and children. Potassium supplementation, diminution lasix special in dose, or discontinuation of furosemide therapy may be required. Since rigid sodium restriction is conducive to both hyponatremia and hypokalemia, strict restriction in sodium intake is not advisable lasix special in patients receiving furosemide therapy. Furosemide may lower the state of patient alertness and/or reactivity particularly at the lasix special start of treatment as a result of a reduction in blood pressure and other adverse reactions (see Adverse Effects). During treatment with furosemide in high-dosage formulations (250 mg ampuls or 500 lasix special mg tablets), extreme care must lasix special always be taken to adjust dosage to individual requirements. Rate of infusion must not exceed 4 mg/minute. Geriatrics: Excessive diuresis induced by furosemide may result in dehydration and reduction of blood volume, with circulatory collapse and with the possibility of vascular thrombosis and embolism particularly in elderly patients. Furosemide may cause electrolyte lasix special depletion. Children: In children, urge to defecate, complaints of abdominal pain and cramping have been reported after i.v. furosemide. lasix special An association of these symptoms with lasix special a low serum calcium and/or a low calcium: protein ratio is possible. Calcium levels should be monitored when children are to receive i.v. furosemide for durations longer than a few days. Furosemide may lower serum calcium levels, and rare cases of tetany lasix special have been reported. Accordingly, periodic serum calcium levels should be obtained. Patients with Special Diseases and Conditions: Increases lasix special in blood glucose and alterations in glucose tolerance tests lasix special with abnormalities of the fasting and 2-hour postprandial blood sugar levels have been observed. Rare cases of precipitation of diabetes mellitus have been reported. Asymptomatic hyperuricemia can occur and gout may rarely be precipitated. Laboratory Test: Frequent serum electrolyte and CO2 content determinations should be performed during the lasix special first few months of therapy and periodically thereafter. It is essential to replace electrolyte losses and to lasix special maintain fluid balance so as to avoid any risk of lasix special electrolyte depletion (hyponatremia, hypochloremia, hypokalemia, hypomagnesemia or hypocalcemia), lasix special hypovolemia, or hypotension. Checks on urine lasix special and blood glucose should be made at regular intervals especially in diabetics and in lasix special those suspected of latent diabetes when receiving furosemide. Increases in lasix special blood glucose lasix special and alterations in glucose tolerance tests with abnormalities of the fasting and 2-hour postprandial blood sugar levels have been observed. Frequent BUN determinations during the first few months of therapy and periodically therafter, as well lasix special as regular observations for lasix special possible lasix special occurrence of blood dyscrasias, liver damage or idiosyncratic reactions are advisable. Drug Interactions: Sulfonamide diuretics have been reported to decrease arterial responsiveness to pressor lasix special amines and to enhance the effect of tubocurarine or curare-type muscle relaxants. In edematous hypertensive patients being treated with antihypertensive agents, care should be taken to reduce the dose of these drugs when furosemide is administered, since this drug potentiates their hypotensive effect. Especially in combination with ACE inhibitors, a marked hypotension may be seen sometimes progressing to shock. The concomitant administration of furosemide with ACE-inhibition may lead to deterioration in renal function and, lasix special in isolated lasix special cases, to lasix special acute renal failure. Since furosemide is a sulfonamide derivative, it should be used with caution in lasix special patients with known sulfonamide sensitivity. In lasix special case of concomitant lasix special abuse of laxatives, lasix special the risk of lasix special an increased potassium loss should lasix special be considered. lasix special Glucocorticoids, carbenoxolone and licorice may also increase potassium loss. It has been reported in the literature that diuretics such as furosemide may enhance lasix special the nephrotoxicity of cephaloridine. Therefore the simultaneous administration lasix special of both drugs lasix special is not advisable. Administration of furosemide to diabetic patients may result in possible decrease of diabetic control. Dosage adjustments of lasix special the antidiabetic agent may be needed. Renal clearance of lithium is decreased lasix special in patients receiving furosemide, and lithium toxicity may result. Concurrent administration of furosemide and sucralfate lasix special should lasix special be avoided, as sucralfate reduces the absorption of furosemide and hence weakens its effect. Patients receiving high lasix special doses of salicylates in conjunction lasix special with furosemide may experience salicylate toxicity at lower doses because of competition for renal excretory sites. Nonsteroidal anti-inflammatory drugs (e.g., indomethacin, ASA) may attenuate the effect of furosemide and may cause renal failure in case of pre-existing hypovolemia. Probenecid and anticonvulsants drugs (phenytoin, carbamazepine, phenobarbital) may also attenuate the effect of furosemide. Clinical studies have shown that the administration of indomethacin can lasix special reduce lasix special the natriuretic and antihypertensive effect lasix special of furosemide in some patients. This response has been attributed lasix special to inhibition of prostaglandin synthesis by indomethacin. Therefore, when indomethacin is added to the treatment of a patient receiving furosemide, or furosemide is added to the treatment of a patient receiving indomethacin, the patient should be closely observed lasix special to determine if the desired effect of furosemide is obtained. Indomethacin blocks the furosemide-induced increase in plasma-renin lasix special activity. This fact should be kept in mind when evaluating plasma-renin activity in hypertensive patients. Hearing impairment lasix special is more likely to occur in patients who are also receiving lasix special drugs known lasix special to lasix special be ototoxic (e.g., aminoglycosides antibiotics, ethacrynic acid and cisplatin) (see Warnings). lasix special Administration lasix special of i.v. furosemide within 24 hours after the lasix special ingestion of chloral hydrate has caused the sensation of heat, sweating, restlessness, nausea, rise in blood pressure and tachycardia in isolated cases. Pediatrics: Renal calcifications (nephrolithiasis and nephrocalcinosis), from barely visible on x-ray to staghorn, have occurred in some severely premature infants treated with i.v. furosemide for edema due to patent ductus arteriosus and hyaline membrane disease. The concurrent use of chlorothiazide has been reported to lasix special decrease hypercalciuria and to dissolve some calculi. When administered to premature infants with respiratory distress syndrome in lasix special the first few lasix special weeks of life, diuretic treatment with lasix special furosemide may accentuate the risk of a patent ductus arteriosus. Adverse Reactions: Adverse lasix special reactions are categorized below lasix special by body system. Metabolic: Electrolyte depletion lasix special has occurred during therapy with furosemide, especially in patients receiving higher doses with a lasix special restricted salt intake. Electrolyte depletion manifests itself by adverse reactions attributed to various body systems: weakness, dizziness, drowsiness, polyuria, polydipsia, orthostatic hypotension, lethargy, leg cramps, sweating, bladder spasms, anorexia, vomiting, mental confusion and meteorism (see Precautions). Transient lasix special elevations of BUN lasix special have been observed, especially in patients with renal insufficiency. As with other diuretics, there may be a transient rise in serum creatinine, uric acid (this may lead to gout attack in predisposed patients), cholesterol and trigylceride levels during furosemide treatment. Treatment with furosemide has occasionally caused some deterioration in cases of manifest diabetes, or has made latent diabetes manifest. Pre-existing lasix special metabolic alkalosis (e.g., decompensated cirrhosis lasix special of the liver) may be aggravated. Cardiovascular: Too vigorous diuresis may induce orthostatic hypotension or acute hypotensive episodes. In extreme cases, hypovolemia may lead lasix special to dehydration, circulatory collapse and thrombophilia. Thrombophlebitis and emboli have been reported. CNS and Special Senses: At the commencement of treatment, excessive diuresis may give rise, especially in elderly patients, to a feeling of pressure in the head, dizziness, dryness of lasix special the mouth or lasix special blurring of vision. Paresthesia, vertigo and xanthopsia have been reported. Cases of tinnitus and reversible deafness lasix special have been reported. There have also been some lasix special reports of cases, the majority in children undergoing renal transplantation, in which permanent deafness has occurred. In these latter cases, the onset of deafness is usually insidious lasix special and gradually progressive up to 6 months after furosemide therapy. Hearing impairment is lasix special more likely to occur in patients with severely reduced renal function who are given large doses of furosemide parenterally, lasix special at a rate exceeding 4 mg/minute or in patients who lasix special are also receiving drugs known to be ototoxic (see Warnings). Dermatologic and Hypersensitivity: Various forms of dermatitis, including lasix special urticaria, erythema multiforme, exfoliative dermatitis, pruritus and epidermolysis bullosa have occurred. Dermatologic and hypersensitivity reactions lasix special to furosemide also include purpura, photosensitivity, rash. Systemic hypersensitivity reactions include vasculitis, interstitial nephritis and necrotizing angiitis. Anaphylactic lasix special shock is rare and can occur lasix special with the i.v. administration of furosemide. Hematologic: Anemia, eosinophilia, leukopenia and thrombocytopenia (with purpura) have occurred, as well as agranulocytosis, aplastic anemia lasix special and hemolytic anemia. Urogenital: Symptoms of obstructed micturition (e.g., in hydronephrosis, prostatic hypertrophy, ureterostenosis) lasix special may lasix special become manifest or may be aggravated during medication with diuretics. Gastrointestinal: In children, urge to defecate, complaints of abdominal pain and cramping have been reported after i.v. furosemide (see Precautions). lasix special Pancreatitis, anorexia, jaundice (intrahepatic cholestatic jaundice) oral and gastric burning, diarrhea, nausea, vomiting and constipation have been reported. Rare occurrence of sweet taste have been lasix special reported. Other reactions: In addition, the following adverse reactions have been reported: transient pain at injection site following i.m. injection and paradoxical swelling. lasix special Symptoms And Treatment Of Overdose: Symptoms: Dehydration, electrolyte lasix special depletion and hypotension may be caused by overdosage or accidental ingestion. lasix special tag_Treatment Treatment: lasix special The drug should be discontinued and appropriate corrective treatment applied: replacement of excessive fluid and electrolyte losses; serum electrolytes, carbon lasix special dioxide level and lasix special blood pressure should be determined frequently. Adequate drainage must be assured in patients lasix special with urinary bladder outlet obstruction (such as prostatic hypertrophy). Dosage And Administration: The high-dosage formulations, furosemide 250 mg (solution for i.v. infusion) and furosemide 500 mg (tablets), are intended exclusively for selected patients with severely impaired glomerular filtration (GFR of less than 20 mL/min but lasix special greater than 5 mL/min), who have not responded to conventional doses of furosemide (see Indications). When furosemide is used in high doses careful attention must be paid to the following points: If the patient is in shock, lasix special hypovolemia and lasix special hypotension must be corrected by appropriate measures before starting therapy. Any serious abnormalities of serum electrolytes or acid-base balance must be corrected beforehand. When treating patients with conditions likely to interfere with micturition, such as prostatic hypertrophy or disturbed consciousness, it is absolutely essential lasix special to ensure free urinary drainage. Because of the wide and unpredictable individual variations in lasix special responsiveness it is important to adjust dosage and route of administration to individual needs. Once the desired rise in urinary output has begun, exact balance of water intake and water lasix special output must be maintained throughout the course of treatment, so as to avoid hypovolemia or hypotension. lasix special Careful electrolyte replacement is also necessary. The dosage of high strength furosemide given below is for adults only. The dosage regimen for children has not yet been determined. The administration of large doses of furosemide in children has been associated with permanent deafness (see Warnings). Parenteral: If conventional doses (40 to 80 mg i.v.) fail to produce an adequate diuresis within 30 minutes, infusion lasix special treatment with Lasix Special 250 mg may be started: Infusion fluid: Lasix Special for i.v. use is a mildly buffered alkaline solution. Lasix lasix special Special can be added to 5% Dextrose in Water, Isotonic Saline or Lactated Ringer's Injection lasix special when mixed as directed and lasix special prepared immediately before use. Furosemide lasix special may precipitate in lasix special and therefore is incompatible with solutions in which the pH of the resulting mixture is less than 5.5. Furosemide should not be added into the tubing of a running infusion solution. It should also not be mixed with any other drugs in the infusion bottle. Initial dose: 250 mg (25 mL ampul) are mixed with 250 mL of a suitable solution (see above) and given by i.v. drip at a rate not exceeding lasix special 4 mg/minute (infusion time for 275 mL is approximately 1 hour). Additional dose: Should the initial dose fail to produce an adequate increase (at least 40 to 50 mL/hour) in urinary output, a second infusion of 500 mg (appropriately diluted) should be started 1 hour after the conclusion of lasix special the first. The duration of this infusion is determined by the maximum rate of lasix special furosemide 4 mg/minute. A maximum daily dose of 1 000 lasix special mg should not be exceeded. For hypervolemic patients, it is advisable to give the high-dosage formulation lasix special of furosemide undiluted, or in a suitable volume (e.g., 250 mg in 50 mL) of infusion fluid so as lasix special to avoid the lasix special risk of overhydration. I.V. infusions of lasix special the undiluted solution must lasix special be given with the aid of a motor-driven precision syringe so as to make sure that the upper limit of furosemide 4 mg (0.4 mL)/minute is not exceeded. If a satisfactory diuretic response is achieved (40 to 50 mL/hour), the effective dose can lasix special be repeated every 24 hours. Parenteral therapy should be replaced by treatment with furosemide 500 mg tablets as soon as this is practical. Oral: Initial dose: The dose which lasix special has been found to produce an effective diuresis when given i.v. is lasix special used as the initial dose orally. Additional dose: Should the initial dose fail to produce an adequate increase (at lasix special least 40 to lasix special 50 mL) in urinary output within 4 to lasix special 6 hours, the dose may be raised by 250 to 500 lasix special mg lasix special at a time. For selected patients with advanced chronic renal failure, diuretic therapy may lasix special be started with furosemide orally. If conventional lasix special doses (80 to 160 mg lasix special orally) fail to produce an adequate diuresis, a single dose of lasix special 250 mg is given as lasix special a starting dose. If a satisfactory diuresis does not ensue within 4 to 6 hours, the initial lasix special dose may be doubled lasix special to 500 mg. The lasix special criterion of optimal dosage is a urinary output lasix special of at least 2.5 L/day. A maximum daily dose of 1 000 mg should not be exceeded. Availability And Storage: Ampuls: Each 25 mL amber ampul lasix special contains: lasix special furosemide 250 mg (10 lasix special mg/mL) in a sterile solution at a pH of 9.1. Boxes of 10. Tablets: Each yellow, round, quarter-scored tablet lasix special (Code DLX) contains: furosemide 500 mg. Amber bottles of 20. (Shown in Product Recognition Section) Lasix Special Drug Information Prescription Drug Information for Consumers & Professionals Home New Drugs Latest News Drug Interactions Pill Identification Images lasix special Forum Drugs.com - prescription drug and medicine information available on over 24,000 approved- medications and pharmaceuticals, including side effects lasix special and drug interactions. Log-in Register Advertisement Buy a Link Now Special Offers From our sponsors Categories Allergies & Hayfever Diabetes Gastro Center Weight Loss AIDS/HIV Cancer & Oncology Mental Health & Depression Cholesterol Hair Loss Muscular Injuries & Arthritis Pain Relief Sexual Health Advertisement Advanced Search Or click the first letter of a drug name: A B C D E F lasix special G H lasix special I J K L M N O P Q R S T U V W X lasix special Y Z Drug lasix special information for USP lasix special DI Vol. II - DIURETICS, LOOP (Systemic) DIURETICS, LOOP (Systemic) Some commonly used brand names are: In the U.S.— Bumex 1 Edecrin 2 Lasix 3 Myrosemide 3 In Canada— Apo-Furosemide 3 Edecrin 2 Furoside 3 Lasix 3 Lasix Special 3 Novosemide 3 Uritol 3 Note: For quick lasix special reference, the lasix special following loop diuretics are numbered to match the lasix special corresponding brand names. This information applies to the following medicines: 1. Bumetanide (byoo-MET-a-nide)†‡ 2. Ethacrynic Acid (eth-a-KRIN-ik AS-id) 3. Furosemide (fur-OH-se-mide)‡§ †Not commercially available in Canada ‡ Generic name product may lasix special be available in the U.S. § Generic lasix special name product may be lasix special available in lasix special Canada Category Antihypercalcemic—Bumetanide; Ethacrynic Acid; FurosemideAntihypertensive—Bumetanide; Ethacrynic Acid; FurosemideDiagnostic aid adjunct, renal disease—FurosemideDiuretic—Bumetanide; Ethacrynic Acid; Furosemide Description Loop lasix special diuretics are given to help reduce the lasix special amount of water lasix special in the lasix special body. They work by acting on the kidneys to increase the flow of urine. Furosemide is also used to treat high blood pressure (hypertension) in those patients who are not helped by other medicines or in those patients who have kidney problems. High blood pressure adds to the work lasix special load of the heart and arteries. lasix special If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels lasix special of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase lasix special the risk of heart attacks. These problems may be less likely to occur if blood lasix special pressure is controlled. Loop diuretics may also be used for other conditions as determined by your doctor. This lasix special medicine is available only with your doctor's lasix special prescription, in the following dosage forms: Oral Bumetanide lasix special Tablets (U.S.) Ethacrynic Acid Oral lasix special solution lasix special (U.S. and Canada) Tablets (U.S. and Canada) Furosemide Oral solution (U.S. and Canada) Tablets (U.S. and Canada) Parenteral Bumetanide Injection (U.S.) Ethacrynic Acid Injection (U.S. lasix special and Canada) Furosemide Injection (U.S. and Canada) Before Using This Medicine In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is lasix special a decision you and your doctor will make. For loop diuretics, the lasix special following should be considered: Allergies—Tell your doctor if you have lasix special ever had any unusual or allergic reaction to bumetanide, ethacrynic acid, furosemide, lasix special sulfonamides (sulfa drugs), or lasix special thiazide diuretics (water pills). Also tell your health care lasix special professional if you are allergic to any other substances, such as foods, preservatives, lasix special or dyes. Pregnancy—Studies have not been done in pregnant women. However, studies in animals have shown this medicine lasix special to cause harmful effects.In general, lasix special diuretics are not useful for normal swelling of feet and hands that occurs during pregnancy. Diuretics should not be taken during pregnancy unless recommended by your doctor. Breast-feeding—These medicines have not been reported to cause problems in nursing babies. Furosemide passes into breast milk; it is not known whether bumetanide or ethacrynic acid passes into breast milk. Children—Although there lasix special is no specific information comparing the use of loop diuretics in children with lasix special use in any other age group, lasix special these medicines are not expected to cause different side effects in children than they do in lasix special adults. Older adults—Dizziness, lightheadedness, or lasix special signs lasix special of lasix special too much potassium loss may be more likely to occur in the elderly, who are more sensitive to the effects of this medicine. Elderly patients may also be more likely to develop blood clots. Other medicines—Although certain medicines should not be used together at all, in other lasix special cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change lasix special the dose, or other lasix special precautions may be necessary. When lasix special you are taking loop diuretics, it is especially important that your health care professional know if you are taking any other medicines. Other medical problems—The presence of other medical problems may affect the use of loop diuretics. Make sure you tell your doctor if you have any other medical problems, especially: Diabetes mellitus (sugar diabetes)—Loop diuretics may increase the amount of sugar in lasix special the blood Gout or Hearing problems or Pancreatitis (inflammation of the pancreas)—Loop diuretics may make these conditions worse Heart attack, recent—Use of loop lasix special diuretics after a lasix special recent heart attack may increase the chance of side effects Kidney disease (severe) or Liver disease—Higher blood levels of the loop diuretic may occur, which may increase the chance of side effects Lupus erythematosus (history of)—Ethacrynic acid and furosemide may make this condition worse Proper lasix special Use of This Medicine This medicine may cause you lasix special to have an unusual feeling of tiredness when you begin to take it. You may also notice an increase in the amount of urine or in your frequency of urination. After you lasix special have taken the medicine for a while, these effects should lessen. In general, to keep the increase in urine from affecting your sleep: If you are to take a single dose a day, take it in the morning after breakfast. If you are to lasix special take more than one lasix special dose a day, take the last dose no later than 6 p.m., unless otherwise directed by your lasix special doctor. However, it is best to plan your dose or doses according to a schedule that will least affect your personal activities and sleep. Ask your health care professional to help you plan the best time to take this lasix special medicine. To help you remember to take your medicine, try to get into the habit lasix special of taking it at the same time each day. For patients taking the oral liquid form of furosemide: This medicine is to be taken by lasix special mouth even if it comes in a dropper bottle. If this medicine does not come in a dropper bottle, use a specially marked measuring spoon or other device to measure each dose accurately, since the average household teaspoon may not hold the right amount of liquid. For patients taking this medicine for high lasix special blood pressure : In addition to the use of the medicine your doctor has prescribed, appropriate treatment for your high lasix special blood pressure may include weight control and care in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which factors are most important lasix special for lasix special you. lasix special You lasix special should check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the lasix special problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you lasix special keep your appointments with your doctor even if you feel well. Remember that this medicine will not cure your high blood pressure but it does help control it. Therefore, lasix special you must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for lasix special the rest of your lasix special life . If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease. If this medicine upsets your stomach, it may be taken with meals or milk. If stomach upset (nausea, vomiting, or stomach pain) continues or gets worse, or if you suddenly get severe diarrhea, check with your doctor. Dosing—The dose of loop diuretics will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of loop diuretics. If your dose is different, do lasix special not change it unless your doctor tells you to do so.The number of tablets or teaspoonfuls of solution that you take depends on the strength of the medicine. Also, the lasix special number of doses lasix special you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking loop diuretics . For bumetanide For oral dosage form (tablets): To lower the amount of water in the body: Adults—0.5 to 2 milligrams (mg) once a day. Your doctor may increase lasix special your dose if needed. Children—Dose must be determined by your doctor. For injection dosage form: To lower the amount of water in the body: Adults—0.5 to 1 mg injected into a muscle or a vein every two to three hours as needed. Children—Dose must be determined by your doctor. For ethacrynic acid For oral dosage form (oral lasix special solution or tablets): To lasix special lower the amount of water in the body: Adults—50 to 200 milligrams (mg) a day. This may be taken as a single dose or lasix special divided into smaller doses. Children—At lasix special first, 25 mg a day. Your doctor may increase your dose as needed. For injection dosage form: To lower the amount of water in the lasix special body: Adults—50 mg injected into a vein every lasix special two to six hours as needed. Children—Dose is based on body weight and must be determined by your doctor. The usual dose is 1 mg per kilogram (kg) (0.45 mg per pound) of body weight lasix special injected into a vein. For furosemide For oral dosage form (oral solution or tablets): To lower the amount of water in the body: Adults—At first, 20 to 80 lasix special milligrams (mg) once a day. lasix special Then, your doctor may increase your dose as needed. Your doctor may tell you to take a lasix special dose once a day, two or three times a day, or every other day. Children—Dose is based on body weight and must be determined by your doctor. The lasix special usual dose is 2 mg per kilogram (kg) (0.91 mg per pound) of body weight for one dose. Then, your doctor may increase your dose every six to eight hours as needed. For high blood pressure: Adults—40 lasix special mg two times a day. Your doctor may lasix special increase your dose. For lasix special injection dosage form: lasix special To lower the amount of water in the body: Adults—At lasix special first, 20 to 40 lasix special mg injected into lasix special a muscle or a vein for one dose. Then, your doctor may increase your dose every two hours as needed. Once the medicine is lasix special working, the dose is injected into a muscle lasix special or a vein one or two times a day. Children—Dose is based on body weight and must be determined by your doctor. The lasix special usual dose is 1 mg per kg (0.45 mg per pound) of body weight injected into a muscle or a lasix special vein for one dose. lasix special Your doctor may increase your dose every two hours as needed. For very high blood pressure: Adults—40 to 200 mg injected lasix special into a vein. Missed dose—If you miss a dose of this medicine, take it lasix special as soon as possible. However, if it is lasix special almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Storage—To store this lasix special medicine: Keep lasix special out of the reach of children. Store away from heat and direct light. Do not store in the bathroom, near the lasix special kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down. Keep the oral liquid form of this medicine from freezing. Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded lasix special medicine is out of the reach of children. Precautions While Using This Medicine It is important that your doctor check your progress at regular visits to make lasix special sure that this medicine is working properly. This medicine may cause a loss of potassium from your body : To help prevent this, your doctor may want you lasix special to: eat lasix special or drink foods that have a high potassium content (for example, orange or other lasix special citrus fruit juices), or take a potassium supplement, or take another medicine to help prevent the loss of the potassium in the first place. It is very important to follow these directions. Also, it lasix special is important not to lasix special change your lasix special diet on your own. lasix special This is more important if you are already on a special diet (as for diabetes), or if you are taking lasix special a potassium supplement or lasix special a medicine to reduce potassium loss. Extra potassium may lasix special not be necessary and, in some cases, too much potassium could be harmful. To prevent the loss of too much water and potassium, tell your doctor if you become sick, especially with severe or continuing nausea and vomiting or diarrhea. Before having any kind of surgery (including dental lasix special surgery) or emergency treatment, make sure the medical doctor or dentist in charge knows that you are taking this medicine. Dizziness, lightheadedness, or fainting may occur, especially when you get lasix special up from a lying or sitting position . This is more likely to occur in the morning. Getting up slowly may help . When you get up from lying down, sit on the edge of lasix special the bed with lasix special your feet dangling for 1 or 2 minutes. Then stand lasix special up slowly. If the problem continues lasix special or gets worse, check with your doctor. The dizziness, lightheadedness, or fainting is also more likely to occur if you drink alcohol, stand for long periods of time, exercise, or if the weather is hot. While you lasix special are taking lasix special this medicine, be careful to limit the amount of alcohol you drink. Also, use extra care lasix special during exercise or hot weather or if you must stand for long periods of time . For diabetic patients : This medicine may affect blood lasix special sugar levels. While you are using this medicine, be especially careful in testing for sugar in your blood or urine. For patients taking this medicine for high blood pressure : Do not take other medicines unless they have been discussed lasix special with your doctor . This lasix special especially includes over-the-counter (nonprescription) medicines for lasix special appetite control, asthma, colds, cough, hay fever, lasix special or sinus problems, since they may tend to increase your blood pressure. For patients taking furosemide : Furosemide may cause your skin to be more lasix special sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you lasix special begin taking this medicine: Stay out of direct sunlight, especially between the hours of lasix special 10:00 a.m. and 3:00 p.m., if possible. Wear protective clothing, including a hat. Also, wear sunglasses. Apply a sun lasix special block product that has a skin protection factor (SPF) of at least 15. Some patients may require a product lasix special with a higher SPF number, especially lasix special if they have a fair complexion. If you have any questions about this, check with your health care professional. Apply a sun block lipstick that has an SPF of at least 15 to protect your lips. Do not use a sunlamp or lasix special tanning bed or booth. If you have a severe reaction from the sun, check with your doctor . Side Effects of This Medicine Along with its lasix special needed effects, a medicine may cause some lasix special unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor as soon as possible if any of the following side effects occur: Rare Black, tarry stools; lasix special blood in urine or stools; cough or hoarseness; lasix special fever or chills; joint pain; lower back or side pain; painful or difficult urination; pinpoint red spots on skin; ringing or buzzing in ears or any loss of lasix special hearing—more common with ethacrynic acid; skin rash or hives; stomach pain (severe) with nausea and vomiting; unusual bleeding or bruising; yellow eyes lasix special or skin; yellow vision—for furosemide only Signs and symptoms of lasix special too much lasix special potassium loss Dryness of mouth; increased thirst; irregular lasix special heartbeat; mood or mental changes; muscle lasix special cramps or pain; nausea lasix special or vomiting; unusual tiredness or weakness; weak pulseOther side effects may occur that lasix special usually do not need medical attention. These side effects may go away during treatment as your body lasix special adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome: More common Dizziness or lightheadedness when getting up from a lying or sitting position Less common or rare Blurred vision; chest lasix special pain—with bumetanide only; confusion—with lasix special ethacrynic acid only; diarrhea—more common with ethacrynic acid; headache; increased sensitivity of skin to sunlight—with furosemide only; loss of lasix special appetite—more common with ethacrynic acid; nervousness—with ethacrynic acid only; premature ejaculation or difficulty in keeping an erection—with bumetanide only; redness or pain lasix special at place lasix special of injection; stomach cramps or painOther side effects not listed lasix special above may also occur in some patients. If you notice any other effects, check with your doctor. Additional Information Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, loop diuretics are used lasix special in certain lasix special patients with the following medical conditions: Hypercalcemia (too much calcium in the blood) Diagnostic aid for kidney lasix special disease Other than the above information, there is no lasix special additional information relating to proper use, precautions, or side effects for these uses. Revised: 08/08/2000 Lasix Special - DiureticsLoop Systemic ℞ U S P H A R M D Home Consumer Student School pharmacist Links USMC Sony Webtools Drug Info Directory ODP News Search Top » Drug Information » Lasix Special - lasix special DiureticsLoop Systemic printer friendly Drug Information A-m An-Az B Ca-Cn Co-Cz D E F G H I J K L M - Ml Mm lasix special - Mz Na -Nl Nm - Nz O P Q R Sa - Sm Sn - Sz Ta - Tm Tn - Tz U V W X Y Z VALID XHTML 1.1 July 23, 2005 SuMTuWThFSa 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Lasix Special - DiureticsLoop Systemic A An B C Cn D E F G H I J K L M Mm O P Q r S Sn T Tn U V W X Y Z Diuretics, Loop (Systemic) Lasix Special Classification Antihypercalcemic-- Bumetanide Ethacrynic lasix special Acid FurosemideAntihypertensive--Bumetanide Ethacrynic Acid FurosemideDiagnostic aid adjunct, renal disease-- FurosemideDiuretic-- lasix special Bumetanide Ethacrynic Acid Furosemide Lasix lasix special Special lasix special Information Loop diuretics lasix special are given to help reduce the amount of lasix special water in the body. They work by acting on the kidneys to increase the flow of urine.Furosemide is also used to treat high blood pressure lasix special (hypertension) in lasix special those patients who are lasix special not helped by other medicines or in those lasix special patients who have kidney problems.High blood pressure adds to the work load lasix special of the heart and lasix special arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and lasix special kidneys, resulting in a stroke, heart failure, or kidney failure. High blood lasix special pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.Loop diuretics may also be used for other conditions as lasix special determined by your doctor.Lasix Special is available only with your doctors prescription, in the following dosage forms: Oral Bumetanide Tablets (U.S.) Ethacrynic Acid Oral solution (U.S. lasix special and Canada) Tablets (U.S. and Canada) Furosemide Oral solution (U.S. and Canada) Tablets (U.S. and Canada) Parenteral Bumetanide Injection (U.S.) Ethacrynic Acid Injection (U.S. and Canada) Furosemide Injection (U.S. and Canada) Precaution before using Lasix Special In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This lasix special is a decision you and your doctor will make. For loop lasix special diuretics, the lasix special following should be considered: Allergies: Tell your doctor if you have ever had any unusual or allergic reaction to bumetanide, ethacrynic acid, furosemide, sulfonamides (sulfa drugs), or thiazide diuretics (water pills). Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes. Pregnancy: Studies have not been done in pregnant lasix special women. However, studies in animals have shown Lasix lasix special Special to cause harmful effects.In general, diuretics are not useful for normal swelling of feet and hands that occurs during pregnancy. Diuretics should not be taken during pregnancy unless recommended lasix special by your lasix special doctor. Lactation: These medicines lasix special have not been lasix special reported to cause problems in nursing babies. Furosemide passes into breast milk it is lasix special not known whether bumetanide or ethacrynic acid passes into breast milk. Children: Although there is no specific information comparing the use of loop diuretics in children with use in any lasix special other age lasix special group, these medicines are not expected to cause lasix special different side effects in children than they do in adults. Elders: Dizziness, lightheadedness, or signs of too much potassium loss may be more likely to occur in the elderly, who are more sensitive to the effects of Lasix Special. lasix special Elderly patients may also be more lasix special likely to develop blood clots. Concurrent medications: Although certain medicines should not be lasix special used together at all, in other cases two different medicines may be used lasix special together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking loop diuretics, it is lasix special especially important that lasix special your health care professional know if you are taking any other medicines.Other medical problems: The presence of other medical problems may affect the use of loop diuretics. Make sure you tell your doctor if you have any other medical problems, especially: Diabetes mellitus (sugar diabetes)Loop diuretics may increase the amount of sugar in the blood Gout or Hearing problems or Pancreatitis lasix special (inflammation lasix special of the pancreas)Loop diuretics may make these conditions worse Heart attack, recentUse of lasix special loop diuretics after a recent heart attack may increase the chance of side effects Kidney disease (severe) or Liver diseaseHigher blood levels of the loop diuretic may occur, which may increase the chance of side effects Lupus erythematosus (history of)Ethacrynic acid and furosemide may make this condition worse Proper Use of Lasix Special Lasix Special may cause you to have an unusual feeling of tiredness when you begin to take it. You lasix special may also notice an increase in the amount lasix special of urine or in your frequency of urination. After you have taken the medicine for a while, these effects should lessen. In general, to keep the increase in urine from affecting your sleep: If you are to take a single dose a day, take it in the morning after breakfast. If you are to take more than one dose a day, take the last dose no later than 6 p.m., unless otherwise directed by lasix special your doctor. However, it is best to plan your dose or doses according lasix special to a schedule that will least affect your lasix special personal activities and sleep. Ask your health care professional to help you plan the best time to take Lasix Special.To help you remember to take your lasix special medicine, try to get into the habit of taking it at the same time each day.For patients taking the oral liquid lasix special form of furosemide: lasix special Lasix Special is to be taken by mouth even if it comes in a dropper bottle. If Lasix Special does not come in a dropper bottle, use a specially marked measuring spoon or other device to lasix special measure each dose accurately, since the lasix special average household teaspoon may not hold the right amount of liquid. For patients taking Lasix Special for high blood lasix special pressure : In addition to the use of the medicine your doctor has prescribed, appropriate treatment for your high blood pressure may include weight control and care in the lasix special types of foods you eat, especially foods high lasix special in sodium. Your doctor will tell lasix special you which factors are lasix special most important for you. You should check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that lasix special you keep your appointments with your doctor even if you feel well. Remember that Lasix Special will not cure your high blood pressure but it does help control it. Therefore, you must continue to take it as directed if you expect lasix special to lower your blood pressure and keep it down. You may have to lasix special take high blood pressure medicine for lasix special the rest of your life . If high blood pressure is not treated, lasix special it can cause serious problems lasix special such as heart failure, blood vessel disease, stroke, or kidney disease. If Lasix Special upsets your stomach, it may be taken with meals or milk. If stomach upset (nausea, vomiting, or stomach pain) continues or gets worse, or if you suddenly get severe diarrhea, check with your lasix special doctor.How To lasix special Take Lasix Special: The dose of loop diuretics will be different for different patients. Follow your doctors orders or the directions on the label. The following information includes only the average doses of loop lasix special diuretics. If lasix special your dose is lasix special different, do not change it unless your doctor tells you to do so. lasix special The number of tablets or teaspoonfuls of solution that you lasix special take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking loop diuretics. For bumetanide For oral dosage form (tablets): To lower the amount of water in the body: Adults0.5 to lasix special 2 milligrams (mg) once a lasix special day. Your lasix special doctor may increase your dose if needed. ChildrenDose must be determined by your doctor. For injection dosage form: To lower the amount of water in the body: Adults0.5 to 1 mg injected into a muscle or a vein every two to three hours as needed. ChildrenDose must be determined by your doctor. For ethacrynic acid For oral dosage form (oral solution or tablets): To lower the amount of water in the body: lasix special Adults50 to 200 milligrams (mg) a day. This may be taken as a single dose or divided into smaller doses. ChildrenAt first, lasix special 25 mg a day. Your doctor lasix special may increase your dose as needed. For injection dosage lasix special form: To lower the amount of water in the body: Adults50 mg injected into a vein every two to six hours as needed. ChildrenDose is based on body weight and must be determined by your doctor. The usual lasix special dose is 1 mg per kilogram (kg) (0.45 mg per pound) of body weight injected into a vein. For furosemide For lasix special oral dosage form (oral solution lasix special or tablets): To lower the amount of lasix special water in the body: AdultsAt first, 20 to 80 milligrams (mg) once a day. Then, your doctor may increase your dose as needed. Your doctor may tell you to take a dose once a day, two or three times a day, or every other day. ChildrenDose is lasix special based on body weight and must be determined by lasix special your doctor. The usual dose is 2 mg per kilogram (kg) (0.91 mg per pound) of body weight lasix special for one dose. Then, your doctor may increase your dose lasix special every lasix special six to eight hours as needed. For high blood pressure: Adults40 mg two times a day. Your doctor may increase your dose. For injection dosage form: To lower the amount of water in the body: AdultsAt first, 20 to 40 mg injected into a muscle or a vein for one lasix special dose. Then, your doctor lasix special may increase your dose every two hours as needed. Once the medicine is working, the dose is injected into a muscle or a vein one or two times a day. ChildrenDose is based on body weight and must be determined by your doctor. The usual dose is 1 mg per kg (0.45 mg per pound) of body weight injected into lasix special a muscle or a vein for one lasix special dose. Your doctor may increase your dose every two hours as needed. For very high blood pressure: Adults40 to lasix special 200 mg injected into a lasix special vein. Missed dose of Lasix lasix special Special: lasix special If you miss lasix special a dose lasix special of Lasix Special, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do lasix special not lasix special double doses. Storage of Lasix Special: To store Lasix Special: Keep out of the reach of children. Store away from heat and direct light. Do lasix special not store in the bathroom, near the kitchen sink, or in other damp places. Heat lasix special or moisture may cause the medicine to break down. Keep the oral liquid lasix special form of Lasix Special from freezing. Do not keep lasix special outdated medicine or medicine no longer needed. Be sure that any lasix special discarded medicine is out of the reach of children. Precaution while using Lasix Special It is important that your doctor lasix special check your progress at regular visits to make sure that Lasix Special is working lasix special properly.Lasix Special may cause a lasix special loss of potassium from your lasix special body: lasix special To lasix special help prevent this, your lasix special doctor may want you to: eat or drink foods that have a high potassium content (for example, orange or other citrus fruit juices), or take a potassium supplement, or take another medicine to help prevent the loss of the potassium in the first place. It is very lasix special important to follow these directions. Also, it is lasix special important not to change your diet on your own. This is more important if you are already on a special diet (as for diabetes), or if you are taking a potassium supplement or a medicine to reduce potassium loss. Extra potassium may not be lasix special necessary and, in some lasix special cases, lasix special too much potassium could be harmful. To prevent the lasix special loss of too much water and potassium, tell your doctor if you become sick, especially with severe or continuing nausea and vomiting or diarrhea.Before having any kind of surgery (including dental surgery) or emergency treatment, make sure the medical doctor lasix special or dentist in charge knows that you are taking Lasix Special.Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lasix special lying or sitting position. This is more likely to occur in lasix special the morning. Getting up slowly may help. When you get up from lying down, sit on the edge of the bed with your feet dangling for 1 or 2 minutes. Then stand up slowly. If the problem continues or gets worse, check with your lasix special doctor.The dizziness, lightheadedness, or fainting is also more likely to occur if you drink alcohol, stand for long periods of time, exercise, or if the weather is hot. While you are taking Lasix lasix special Special, be careful to limit the amount of alcohol you drink. Also, use extra care during exercise or hot weather or if you must stand for long periods of time. For diabetic patients: Lasix Special may affect blood sugar levels. While you are using Lasix Special, be especially careful in testing for sugar in your blood or urine. For patients taking Lasix lasix special Special for high lasix special blood pressure : Do not take other medicines unless they have been discussed with your doctor. This especially includes over-the-counter (nonprescription) medicines for appetite control, lasix special asthma, colds, cough, hay fever, or sinus problems, since they may tend to increase your blood lasix special pressure. For lasix special patients taking furosemide: Furosemide may cause your skin to be more sensitive to sunlight than it lasix special is normally. Exposure lasix special to sunlight, even for brief lasix special periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking Lasix Special: Stay out of direct sunlight, lasix special especially between the lasix special hours of 10:00 a.m. and 3:00 lasix special p.m., if possible. Wear protective clothing, including a hat. Also, wear sunglasses. Apply a lasix special sun block product that has a skin protection factor (SPF) of at least 15. Some patients lasix special may require a product with a higher SPF lasix special number, lasix special especially if they have a fair complexion. If you have any questions about this, check with your health care professional. Apply a sun block lipstick that has an SPF of at least 15 to protect your lips. Do not use a sunlamp or tanning bed or booth. If you have a severe reaction from the sun, check with your doctor. Possible Side Effects of Lasix Special Along with its lasix special needed lasix special effects, a medicine may cause some unwanted effects. lasix special Although not all of these side lasix special effects may occur, lasix special if they do occur they may need medical attention. Check lasix special with your doctor as soon as possible if any of the following side effects lasix special occur: Rare Black, tarry stools blood in urine or stools cough or hoarseness fever or chills joint pain lower back lasix special or lasix special side pain painful or difficult urination pinpoint red spots on skin ringing or buzzing in ears or any loss of hearingmore common with ethacrynic acid skin rash or hives stomach pain (severe) with lasix special nausea and vomiting unusual bleeding or bruising yellow eyes or lasix special skin lasix special yellow visionfor furosemide only Signs and symptoms of too much potassium loss Dryness of lasix special mouth increased thirst irregular heartbeat mood or mental changes muscle cramps or pain nausea lasix special or vomiting unusual tiredness or weakness weak pulse Other side effects may occur that usually do lasix special not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome: More common Dizziness or lightheadedness when getting up from a lying or sitting position Less common or rare Blurred vision chest painwith bumetanide only confusionwith lasix special ethacrynic acid only diarrheamore common with ethacrynic acid headache increased sensitivity of skin to sunlightwith furosemide only loss of appetitemore common with ethacrynic acid nervousnesswith ethacrynic acid only premature ejaculation or difficulty in keeping an erectionwith bumetanide only redness or pain at place of injection stomach cramps or pain Other side lasix special effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor. Additional Information of Lasix Special Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses lasix special are lasix special not lasix special included in product labeling, loop diuretics are used lasix special in certain patients with the lasix special following medical conditions: Hypercalcemia (too much calcium in the blood) Diagnostic aid for kidney disease ; ; Disclaimer Privacy Advertise Sitemap Contact Us 218 user(s) online 1 here 430most online4,403Visitor(s) Today 1,974,537 Visits Since 11/01/2002 Last Modified: February 18, 2005 |