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| Hydrochlorothiazide Adverse effects from hydrochlorothiazide What is hydrochlorothiazide Hydrochlorothiazide triamterene Hydrochlorothiazide side effects Hydrochlorothiazide and erections Hydrochlorothiazide dosage Does hydrochlorothiazide cause hyperglycemia Hydrochlorothiazide use Triamterene and hydrochlorothiazide and side effects Bleeding and hemorrhoids and hydrochlorothiazide Hydrochlorothiazide dosage menieres Lisonpril hydrochlorothiazide side effects Side effects from hydrochlorothiazide Spc felodipine hydrochlorothiazide | Hydrochlorothiazide Side Effects Effects of hydrochlorothiazide of Hydrochlorothiazide Side Effects of Hydrochlorothiazide Flash-Med Home Page Hydrochlorothiazide Review Questions and Answers Generic Names: Effects of hydrochlorothiazide What are the side effects of Effects of hydrochlorothiazide Hydrochlorothiazide? What are the side effects for Hydrochlorothiazide? The side effects of hydrochlorothiazide Effects of hydrochlorothiazide include potassium wasting, hypercalcemia, hypomagnesemia, metabolic alkalosis, hyponatremia, hyperuricemia, hyperglycemia, hypercholesterolemia, hypertriglyceridemia. How is Hydrochlorothiazide excreted? Hydrochlorothiazide is secreted by the kidneys at the proximal tubule. Adverse events in people taking with Hydrochlorothiazide Gastrointestinal .... Metabolic Hypokalemia, metabolic alkalosis, hypercalcemia, hypomagnesemia, hyperuricemia, hyponatremia Cardiac Hypercholesterolemia, Hypertriglyceridemia Genitourinary ... Pulmonary ... Endocrine Hyperglycemia Hematologic ... Pharmacology - Hydrochlorothiazide Question: How Effects of hydrochlorothiazide does hydrochlorothiazide change potassium homeostasis? Answer: Hydrochlorothiazide can result in decreased potassium levels. Question: How does hydrochlorothiazide change magnesium homeostasis? Answer: Hydrochlorothiazide can result in decreased magnesium levels. Question: Can hydrochlorothiazide be used in patients with renal insufficiency? Answer: Hydrochlorothiazide is not effective as an antihypertensive in patients with a creatinine clearance of less than 50 ml per minute. Question: How Effects of hydrochlorothiazide does hydrochlorothiazide change serum calcium Effects of hydrochlorothiazide levels? Answer: Hydrochlorothiazide can result in increases in the calcium level. Question: How does Effects of hydrochlorothiazide hydrochlorothiazide change uric acid metabolism? Answer: Hydrochlorothiazide is associated with hyperuricemia. Question: What is the mechanism of hydrochlorothiazide? Answer: Hydrochlorothiazide increases the water in sodium excretion resulting Effects of hydrochlorothiazide in a decrease in blood pressure. hydrochlorothiazide Effects of hydrochlorothiazide Side Effects, Interactions and Information - Drugs.com Prescription Drug Effects of hydrochlorothiazide Information for Consumers & Professionals Home New Drugs Latest News Drug Interactions Pill Identification Images Forum Drugs.com - prescription drug and medicine information available on over 24,000 approved- medications and pharmaceuticals, including side effects and drug interactions. Log-in Register Advertisement Buy a Link Now Special Offers Categories Allergies & Hayfever Diabetes Gastro Center Weight Loss AIDS/HIV Cancer & Oncology Mental Health & Depression Cholesterol Hair Loss Muscular Injuries & Arthritis Pain Relief Sexual Health From our sponsors Advertisement Recent Drug Searches Phentermine Lamictal Cialis Fosamax Bextra Nexium Doxycycline Hylaform Plus Zanaflex Oxycontin Effects of hydrochlorothiazide Advanced Search Or click the first letter of a drug name: A B C D E F G H I J K L M N O Effects of hydrochlorothiazide P Effects of hydrochlorothiazide Q R S T U V W X Y Z HYDROCHLOROTHIAZIDE Generic Name: hydrochlorothiazide (hye dro klor oh THYE a zide)Brand Names: Carozide, Diaqua, Esidrix, Ezide, Hydro Par, HydroDIURIL, Loqua, Microzide, Oretic What Effects of hydrochlorothiazide is the most important information I should know about hydrochlorothiazide? • To reduce nighttime urination, take hydrochlorothiazide early in the day unless otherwise directed by your doctor. • Use caution when driving, operating machinery, or performing other hazardous activities. Hydrochlorothiazide may cause dizziness. If you Effects of hydrochlorothiazide experience dizziness, avoid these activities. What is hydrochlorothiazide? • Hydrochlorothiazide is a thiazide diuretic (water pill). It decreases the amount of fluid in the body by increasing the amount of salt and water lost in the urine. • Hydrochlorothiazide is used to lower blood pressure and to decrease edema (swelling). • Hydrochlorothiazide may also be used for purposes other than those listed Effects of hydrochlorothiazide in Effects of hydrochlorothiazide this medication guide. What should I discuss with my healthcare provider before taking hydrochlorothiazide? • Do Effects of hydrochlorothiazide not take hydrochlorothiazide without first talking to your doctor if you have an allergy to sulfa-based drugs such as sulfa antibiotics. You may have an allergic reaction to hydrochlorothiazide. • Before taking hydrochlorothiazide, tell your doctor if you have · diabetes; · gout; · a collagen vascular disease such as systemic lupus erythematosus; · pancreatitis; · kidney disease; · liver disease; or · high levels of cholesterol or Effects of hydrochlorothiazide triglycerides (types of fat) in your blood. • You may need a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above. • Hydrochlorothiazide is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Effects of hydrochlorothiazide Do not take hydrochlorothiazide without first talking to your doctor if you are pregnant or could become pregnant during treatment. • Hydrochlorothiazide passes into breast milk and may affect a nursing infant. Do not take hydrochlorothiazide without first talking to your doctor if you are breast-feeding a baby. How should I take hydrochlorothiazide? • Take hydrochlorothiazide exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. • Take each dose with a full glass of water. • To reduce nighttime urination, take hydrochlorothiazide early in the day unless Effects of hydrochlorothiazide otherwise directed by your doctor. • It is important to Effects of hydrochlorothiazide take hydrochlorothiazide regularly to get the most benefit. • Do not stop taking hydrochlorothiazide suddenly even if Effects of hydrochlorothiazide you feel better. Stopping suddenly could make your condition worse. • Your doctor may want you to have blood pressure monitoring or other medical evaluations during treatment with hydrochlorothiazide to monitor progress and side effects. • Store this medication at room temperature away from moisture and heat. What happens if I Effects of hydrochlorothiazide miss a dose? • Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication. What happens if I overdose? • Seek emergency medical attention if an overdose is suspected. • Symptoms of a hydrochlorothiazide overdose include increased urination, nausea, vomiting, diarrhea, fatigue, lethargy, and unconsciousness. What should I avoid while Effects of hydrochlorothiazide taking hydrochlorothiazide? • Use caution when driving, operating machinery, or performing other hazardous activities. Hydrochlorothiazide may cause dizziness. If you experience dizziness, avoid these activities. • Use alcohol cautiously. Alcohol may increase the side effects of hydrochlorothiazide. • Avoid a diet high in salt. Too much salt may cause the body to retain water and may decrease the effects of hydrochlorothiazide. • Avoid prolonged exposure to sunlight. Hydrochlorothiazide may increase the sensitivity of Effects of hydrochlorothiazide the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. • Avoid becoming overheated in hot weather and during exercise. It Effects of hydrochlorothiazide is easier to become dangerously dehydrated while taking hydrochlorothiazide. What are the possible side effects of hydrochlorothiazide? • If you experience any of the following serious side effects, stop taking hydrochlorothiazide and seek emergency medical attention or contact your Effects of hydrochlorothiazide doctor immediately: · an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); · unusual fatigue; · abnormal bleeding or bruising; · yellow skin or eyes; · confusion; · irregular heartbeats or a fluttering feeling in the chest; or · little or no urine. • Other, Effects of hydrochlorothiazide less serious Effects of hydrochlorothiazide side effects are more likely to occur. Continue to take hydrochlorothiazide and talk to your doctor if you experience · dizziness, especially when rising from sitting or lying down; · tingling or numbness in the arms, legs, hands, or feet; · excessive urination; · muscle weakness or cramps; · increased hunger or thirst; · nausea or decreased appetite; · abdominal pain; · sensitivity to sunlight; or · impotence. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect hydrochlorothiazide? • Before taking hydrochlorothiazide tell your doctor if you are taking any of the following medications: · lithium (Lithobid, Eskalith, others); · digoxin (Lanoxin, Lanoxicaps); · the cholesterol-lowering drugs cholestyramine (Questran) or colestipol (Colestid); · a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin), naproxen (Naprosyn, Anaprox, Aleve), ketoprofen (Orudis, Orudis KT, Oruvail), indomethacin (Indocin), diclofenac (Cataflam, Voltaren), etodolac (Lodine), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), fenoprofen (Nalfon), ketorolac (Toradol), or flurbiprofen (Ansaid); · a diabetes medication such as glipizide (Glucotrol), glyburide (Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase), tolbutamide (Orinase), and others; or · a steroid medicine such as cortisone (Cortone), Effects of hydrochlorothiazide dexamethasone (Decadron, Hexadrol), hydrocortisone (Cortef, Hydrocortone), prednisone (Orasone, Deltasone), prednisolone (Delta Cortef, Prelone), methylprednisolone (Medrol), and others. • You may not be able Effects of hydrochlorothiazide to take hydrochlorothiazide, or you may require a dosage adjustment Effects of hydrochlorothiazide or special monitoring during treatment if you are taking any Effects of hydrochlorothiazide of the medications listed above. • Also, before taking hydrochlorothiazide, tell your Effects of hydrochlorothiazide doctor if you are taking any other medicine to treat high blood pressure, water retention, heart problems, prostate problems, or another condition. Some medicines Effects of hydrochlorothiazide used to treat these conditions may interact with Effects of hydrochlorothiazide hydrochlorothiazide and the effects on your heart may be increased. • Hydrochlorothiazide may increase the effects of other drugs that cause drowsiness, including sedatives (used to treat insomnia), pain relievers, seizure medicines, antidepressants, alcohol, antihistamines, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor. • Drugs other than those listed here may also interact with hydrochlorothiazide or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products. Where can I get more information? • Your pharmacist has additional information about hydrochlorothiazide written for health professionals that you may read. • Remember, keep this and all other Effects of hydrochlorothiazide medicines out of the reach of children, Effects of hydrochlorothiazide never share your medicines with others, and Effects of hydrochlorothiazide use this medication only for the indication Effects of hydrochlorothiazide prescribed. • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, Effects of hydrochlorothiazide unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/ or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any Effects of hydrochlorothiazide given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, Effects of hydrochlorothiazide warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2004 Cerner Multum, Inc. Version: 5.04. Revision Date: 1/ 23/ 04. Search the Internet for hydrochlorothiazide Search for drug interactions Ask questions/find answers in the Drugs.com Community Please help us keep this valuable resource alive! MULTUM is a leading provider of Effects of hydrochlorothiazide electronic and printed information for professionals and consumers in healthcare and industry. MULTUM employs physicians, pharmacists, software engineers, account executives, and product Effects of hydrochlorothiazide managers whose collective expertise produces the most current, comprehensive drug information available. The information contained in MULTUM data is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment.View full disclaimer Search again By Drug Name Condition The Internet Advanced Search Popular Searches Lipitor Viagra Cialis Levitra Zoloft Hair Transplant Health Insurance Healthy Diet Lose Weight Pain Relief Advertisement ADVERTISEMENTHome - Professional - Drug Interactions - Pill Identification - Image Search - Help - Question.com Advertisers - FAQs - Links - Privacy Policy - Terms of Use - Contact Us - Top Drugs - Merchandise Store - About Drugs.comThe drugs.com drug database is powered by MicromedexTM and MultumTM. Micromedex data last updated 6 June 2005. Effects of hydrochlorothiazide Micromedex Physicians Desk Reference data last updated 18 May 2005.Multum data last updated 28 June 2005. © Copyright 2005 Drugs.com We subscribe to the HONcode principles.Verify here. Hydrochlorothiazide Information from Drugs.com Prescription Drug Information for Consumers & Professionals Home New Drugs Latest News Drug Interactions Pill Identification Effects of hydrochlorothiazide Images Forum Drugs.com - prescription drug and medicine information available on over 24,000 approved- medications and pharmaceuticals, including side effects and drug interactions. Log-in Register Advertisement Buy a Link Now Special Offers From our sponsors Categories Allergies & Hayfever Diabetes Gastro Center Weight Loss AIDS/HIV Cancer & Oncology Mental Health & Depression Cholesterol Hair Loss Muscular Injuries & Arthritis Pain Relief Sexual Health Advertisement Recent Drug Searches Flexeril Zetia Ertaczo Cialis Apokyn Entex Inderal Combunox Ativan Epivir Advanced Search Or click the first letter of a drug name: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z hydrochlorothiazide(hye dro klor oh THYE a zide)Carozide, Diaqua, Esidrix, Ezide, Hydro Par, HydroDIURIL, Loqua, Microzide, Oretic What is the most important information I should know about hydrochlorothiazide? • To reduce nighttime urination, take hydrochlorothiazide early in the day unless otherwise directed by your doctor. • Use caution when driving, operating machinery, or performing other hazardous activities. Hydrochlorothiazide may cause dizziness. If you experience dizziness, avoid these activities. What Effects of hydrochlorothiazide is hydrochlorothiazide? • Hydrochlorothiazide is a thiazide diuretic (water pill). It decreases the amount of fluid in your Effects of hydrochlorothiazide body by increasing the amount of salt and water you lose in your Effects of hydrochlorothiazide urine. • Hydrochlorothiazide is used to lower blood pressure and to decrease edema (swelling). • Hydrochlorothiazide may also be used for purposes other than those listed in this medication guide. Who should not take hydrochlorothiazide? • Do not take hydrochlorothiazide without first talking to your doctor if you have an allergy to sulfa-based drugs such Effects of hydrochlorothiazide as sulfa antibiotics. You may have an allergic Effects of hydrochlorothiazide reaction to hydrochlorothiazide. • Before taking hydrochlorothiazide, tell your doctor if you have · diabetes, · gout, · a collagen vascular disease such as systemic lupus erythematosus, · pancreatitis, · kidney disease, · liver disease, or · high levels of cholesterol or triglycerides (types of fat) in your blood. • You may need a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above. • Hydrochlorothiazide is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take hydrochlorothiazide without first talking to your doctor if you are pregnant. • Hydrochlorothiazide passes into breast milk and may harm a nursing infant. Do not take hydrochlorothiazide without first talking to your doctor if you are breast-feeding a baby. Effects of hydrochlorothiazide How should I take hydrochlorothiazide? • Take hydrochlorothiazide exactly as directed by your doctor. If you do not understand these directions, ask Effects of hydrochlorothiazide your pharmacist, nurse, or doctor to explain them to you. • Take each dose with a full glass of Effects of hydrochlorothiazide water. • To reduce nighttime urination, take hydrochlorothiazide early Effects of hydrochlorothiazide in the day unless otherwise directed by your doctor. • Do not stop taking Effects of hydrochlorothiazide hydrochlorothiazide suddenly even if you feel better. Stopping suddenly could make your condition worse. • Store this medication Effects of hydrochlorothiazide at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. However, if it is almost time for your Effects of hydrochlorothiazide next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication. What happens if I overdose? • Seek emergency medical attention. • Symptoms of a hydrochlorothiazide overdose include increased urination, nausea, vomiting, diarrhea, fatigue, lethargy, and unconsciousness. What should I avoid while taking hydrochlorothiazide? • Use caution when driving, operating machinery, or performing other hazardous activities. Hydrochlorothiazide may cause dizziness. If you experience dizziness, avoid these Effects of hydrochlorothiazide activities. • Use alcohol cautiously. Alcohol may increase the side effects of hydrochlorothiazide. • Avoid a Effects of hydrochlorothiazide diet high in salt. Too much salt may cause your body to retain water and may decrease the effects of hydrochlorothiazide. • Avoid prolonged exposure to sunlight. Hydrochlorothiazide may increase the sensitivity of your skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. • Avoid becoming overheated in hot weather and during exercise. It is easier to become dangerously dehydrated while taking hydrochlorothiazide. What are the possible side effects of hydrochlorothiazide? • If you experience any of the following serious side Effects of hydrochlorothiazide effects, stop taking hydrochlorothiazide and seek emergency medical attention: · an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; Effects of hydrochlorothiazide or hives); · unusual fatigue; · abnormal bleeding or bruising; · yellow skin or eyes; Effects of hydrochlorothiazide · confusion; · irregular heartbeats or a fluttering feeling in Effects of hydrochlorothiazide your chest; or · little or no urine. • Other, less Effects of hydrochlorothiazide serious side effects are more likely to occur. Continue to take hydrochlorothiazide and talk to your doctor if you experience · dizziness, especially when you switch to sitting or standing from a lying Effects of hydrochlorothiazide position; · tingling or numbness in your arms, legs, hands, or feet; · excessive urination; · muscle weakness or cramps; · increased hunger or thirst; · nausea or decreased appetite; · abdominal pain; · sensitivity to sunlight; or · impotence. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect Effects of hydrochlorothiazide that seems unusual or that is especially bothersome. What other drugs will affect hydrochlorothiazide? • Before taking hydrochlorothiazide tell your doctor if you are taking any of Effects of hydrochlorothiazide the following medications: · lithium (Lithobid, Eskalith, others); · digoxin (Lanoxin, Lanoxicaps); · the cholesterol-lowering drugs cholestyramine (Questran) or colestipol (Colestid); · a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin), naproxen (Naprosyn, Anaprox, Aleve), ketoprofen (Orudis, Orudis KT, Oruvail), indomethacin (Indocin), diclofenac (Cataflam, Voltaren), etodolac (Lodine), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), fenoprofen (Nalfon), ketorolac (Toradol), or flurbiprofen (Ansaid); · a diabetes medication such as glipizide (Glucotrol), glyburide (Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase), tolbutamide Effects of hydrochlorothiazide (Orinase), and others; or · a steroid medicine such as cortisone (Cortone), dexamethasone (Decadron, Hexadrol), hydrocortisone (Cortef, Hydrocortone), prednisone (Orasone, Deltasone), prednisolone (Delta Cortef, Prelone), methylprednisolone (Medrol), and others. • You may not be able to take hydrochlorothiazide, or Effects of hydrochlorothiazide you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medications listed above. • Also, before taking hydrochlorothiazide, tell your doctor if you Effects of hydrochlorothiazide are Effects of hydrochlorothiazide taking any other medicine to treat high blood pressure, water retention, heart problems, prostate problems, or another Effects of hydrochlorothiazide condition. Some medicines used to treat these conditions may interact with hydrochlorothiazide and the effects on your heart may be increased. • Hydrochlorothiazide may increase the effects of other drugs that cause drowsiness, including sedatives (used to treat insomnia), pain relievers, seizure medicines, antidepressants, alcohol, antihistamines, anxiety medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor. • Drugs other than those listed here may also interact with hydrochlorothiazide or affect your condition. Talk to your doctor and pharmacist before taking any Effects of hydrochlorothiazide prescription Effects of hydrochlorothiazide or over-the-counter medicines. Where can I get more information? • Your pharmacist has additional information about hydrochlorothiazide Effects of hydrochlorothiazide written for health professionals that you may Effects of hydrochlorothiazide read. • Remember, keep this and Effects of hydrochlorothiazide all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. • Every effort has been made to ensure that the information provided by Cerner Multum, Inc. Effects of hydrochlorothiazide ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse Effects of hydrochlorothiazide drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given Effects of hydrochlorothiazide drug or drug combination in no way should be construed Effects of hydrochlorothiazide to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2003 Cerner Multum, Inc. Version: 5.02. Revision Date: 2/14/03. Popular Searches LipitorViagra Cialis Levitra Zoloft Hair Transplant Health Insurance Healthy Diet Lose Weight Pain Relief Advertisement ADVERTISEMENT Home - Effects of hydrochlorothiazide Drug Interactions - Pill Identifier - Image Search - Latest News - New Drugs - Forum Advertisers - FAQs - Links - Privacy Policy - Terms of Use - Contact Us - Top Drugs - Merchandise Store - About Drugs.comThe drugs.com drug database is powered by MicromedexTM and MultumTM. Micromedex data last updated 6 June 2005.Micromedex Physicians Desk Reference data last updated 18 May 2005.Multum data last updated 28 June Effects of hydrochlorothiazide 2005.© Copyright 2005 Drugs.com We subscribe to the HONcode principles. Verify here. Entrez PubMed My NCBI[Sign In] [Register] All Databases PubMed Nucleotide Protein Genome Structure OMIM PMC Journals Books Search PubMed Protein Nucleotide Structure Genome Books CancerChromosomes Conserved Domains 3D Domains Gene Genome Project GENSAT GEO Profiles GEO Effects of hydrochlorothiazide DataSets HomoloGene Journals MeSH NCBI Web Site NLM Catalog OMIM PMC PopSet Probe PubChem BioAssay PubChem Compound PubChem Substance SNP Taxonomy UniGene UniSTS for Limits Preview/Index History Clipboard Details About Entrez Text Version Entrez PubMed Overview Help | FAQ Tutorial New/Noteworthy E-Utilities PubMed Services Journals Database MeSH Database Single Citation Matcher Batch Citation Matcher Clinical Queries Special Queries LinkOut My NCBI (Cubby) Related Resources Order Documents NLM Catalog NLM Gateway TOXNET Consumer Health Clinical Alerts ClinicalTrials.gov PubMed Central Display Summary Brief Abstract Citation MEDLINE XML UI List LinkOut ASN.1 Related Articles Cited Articles Cited in Books CancerChrom Links Domain Links 3D Domain Links GEO DataSet Links Gene Links Gene (GeneRIF) Links Genome Links Project Links GENSAT Links GEO Profile Links HomoloGene Links Nucleotide Links OMIM Links BioAssay Links Compound Links Compound via MeSH Substance Links Substance via MeSH PMC Links Cited in PMC PopSet Links Probe Links Protein Links SNP Links Structure Links UniGene Links UniSTS Links Show 5 10 20 50 100 200 500 Sort by Author Journal Pub Date Send to Text File Clipboard E-mail Order All: 1 Review: 0 1: Diabet Med. 2003 Sep;20(9):708-12. Related Articles, Links Comparative metabolic effects of hydrochlorothiazide and Effects of hydrochlorothiazide indapamide in Effects of hydrochlorothiazide hypertensive diabetic patients receiving ACE inhibitor therapy.Krum H, Skiba Effects of hydrochlorothiazide M, Gilbert RE.National Health & Medical Research Council of Australia Centre of Clinical Effects of hydrochlorothiazide Research Excellence in Therapeutics, Effects of hydrochlorothiazide Department of Epidemiology & Preventive Medicine, Monash University/Alfred Hospital, Prahran, Victoria, Australia. henry.krum@med.monash.edu.auBACKGROUND: ACE inhibitors, when used as monotherapy, are frequently unable to adequately control blood pressure in diabetic patients. A diuretic may be added; however, thiazide diuretics, but not indapamide, have been associated with adverse metabolic effects. Whether these Effects of hydrochlorothiazide effects also apply to thiazides when administered in the currently used lower doses, and whether they differ from indapamide in their metabolic effects, particularly when used in combination with an ACE inhibitor in diabetic patients, has not been previously studied. METHODS: We conducted a prospective, randomized, open-label, blinded endpoint crossover study comparing the metabolic responses to the addition of either hydrochlorothiazide (HCTZ) or indapamide, in 18 diabetic hypertensive patients receiving ACE inhibitor monotherapy for hypertension. Patients stabilized on fosinopril 20 mg/day were randomized to receive either HCTZ 12.5 mg od or indapamide 2.5 mg Effects of hydrochlorothiazide od for 8 weeks, then crossed over to the alternate therapy for a further 8-week period. Blood pressure, heart rate and metabolic assessments were performed at the end of each 8-week treatment period. RESULTS: Seated and standing systolic and diastolic blood pressures were not different Effects of hydrochlorothiazide between HCTZ or indapamide when added to fosinopril, nor was the fasting lipid profile or urinary albumin : creatinine ratio. Plasma potassium was lower with indapamide compared with HCTZ treatment (indapamide 4.3+/-0.1 mmol/l; HCTZ 4.5+/-0.1 mmol/l, P<0.01) and HbA1c was higher with indapamide than with HCTZ therapy (indapamide 7.8+/-0.4%; HCTZ 7.2+/-0.3%, P<0.01). CONCLUSIONS: Hydrochlorothiazide 12.5 mg/day, when added to background ACE inhibitor therapy with fosinopril in hypertensive diabetic patients, resulted in a metabolic Effects of hydrochlorothiazide profile that was similar, if not superior on certain parameters, in comparison with indapamide 2.5 mg/day.Publication Types: Clinical Trial Multicenter Study Randomized Controlled Trial PMID: 12925048 [PubMed - indexed for MEDLINE] Display Summary Brief Abstract Citation MEDLINE XML UI List LinkOut ASN.1 Related Articles Cited Articles Cited in Books CancerChrom Links Domain Links 3D Domain Links GEO DataSet Links Gene Links Gene (GeneRIF) Links Genome Links Project Links GENSAT Links GEO Profile Links HomoloGene Links Nucleotide Links OMIM Links BioAssay Links Compound Links Compound via MeSH Substance Links Substance via MeSH PMC Links Cited in PMC PopSet Links Probe Links Protein Links SNP Links Structure Links UniGene Links UniSTS Links Show 5 10 20 50 100 200 500 Sort by Author Journal Pub Date Send to Text File Clipboard E-mail Order Write to the Help Desk NCBI | NLM | NIH Department of Health & Human Services Privacy Statement | Freedom of Information Act | Disclaimer Jul 18 2005 15:16:48 effects of drug lopressor side effects |