a selective serotonin reuptake inhibitor (SSRI) used to treat depression,
panic attacks, obsessive compulsive disorders (OCD) and post-traumatic stress
disorder. This medication works by helping to restore the balance of certain
natural chemicals in the brain.
Drug Information
IMPORTANT NOTE:
The following information is intended to supplement, not substitute for, the
expertise and judgment of your physician, pharmacist or other healthcare professional.
It should not be construed to indicate that use of the drug is safe, appropriate,
or effective for you. Consult your healthcare professional before using this
drug.
Uses
Sertraline is used to treat depression, panic attacks, obsessive compulsive
disorders (OCD), and post-traumatic stress disorder (PTSD). This medication
works by helping to restore the balance of certain natural chemicals in the
brain.
How to Use
Take medication by mouth usually once daily with or without food; or as directed
by your doctor. It is recommended that you take your dosage at the same time
each day, either in the morning or in the evening. The dosage is based on
your medical condition and response to therapy. It is important to continue
taking this medication as prescribed even if you feel well. Also, do not stop
taking this medication without consulting your doctor. It may take up to 4
weeks before the full benefit of this drug takes effect.
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Side Effects
Nausea, headache, diarrhea, trouble sleeping, dry mouth, drowsiness, dizziness,
or upset stomach may occur. If any of these effects persist or worsen, notify
your doctor promptly. Tell your doctor immediately if any of these serious
side effects occur: loss of appetite, unusual weight loss, unusual or severe
mental/mood changes, increased sweating/flushing, unusual fatigue, uncontrolled
movements (tremor), decreased interest in sex. An allergic reaction to this
drug is unlikely, but seek immediate medical attention if it occurs. Symptoms
of an allergic reaction include: rash, itching, swelling, severe dizziness,
trouble breathing. If you notice other effects not listed above, contact your
doctor or pharmacist. Tell your doctor immediately if any of these unlikely
but serious side effects occur: vision changes, changes in sexual ability,
painful and/or prolonged erection. Tell your doctor immediately if any of
these highly unlikely but very serious side effects occur: fainting, irregular
heartbeat, chest pain, muscle pain, trouble swallowing, ringing in in the
ears, seizures.
Precautions
Tell your doctor your medical history, especially of: liver problems, kidney
disease, seizures, heart problems, any allergies. This drug may make you dizzy
or drowsy; use caution engaging in activities requiring alertness such as driving
or using machinery. Limit alcoholic beverages. Caution is advised when using
in the elderly because they may be more sensitive to the effects of the drug.
This medication should be used only when clearly needed during pregnancy. Discuss
the risks and benefits with your doctor. This drug passes into breast milk.
Because of the potential risk to the infant, breast-feeding while using this
drug is not recommended. Consult your doctor before breast-feeding. other SSRI
antidepressants (e.g., citalopram, fluoxetine), nefazodone, venlafaxine, "triptan"
migraine drugs (e.g., sumatriptan, zolmitriptan), tramadol, tricyclic antidepressants
(e.g., amitriptyline, nortriptyline), cimetidine, flecainide, propafenone, clozapine,
trazodone, lithium, tryptophan, "blood thinners" (e.g., warfarin),
any herbal/natural products (e.g., melatonin, St John's wort, ayahuasca). Tell
your doctor if you take any drugs that cause drowsiness such as: medicine for
sleep, sedatives, tranquilizers, anti- anxiety drugs (e.g., diazepam), narcotic
pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines
such as chlorpromazine), anti-seizure drugs (e.g., carbamazepine), muscle relaxants,
certain antihistamines (e.g., diphenhydramine). Report other drugs which affect
the heart rhythm (QTc prolongation), such as: dofetilide, pimozide, sotalol,
quinidine, procainamide, sparfloxacin, "water pills" (diuretics such
as furosemide or hydrochlorothiazide). Ask your doctor or pharmacist for more
details. Do not start or stop any medicine without doctor or pharmacist approval.
Drug Interactions
Certain medications taken with could result in serious, even fatal, drug interactions.
Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide,
phenelzine, procarbazine, selegiline, tranylcypromine) within 2 weeks before
or after treatment with this medication. Consult your doctor or pharmacist for
additional information. is not recommended for use with: weight loss drugs (e.g.,
sibutramine, phentermine), terfenadine, astemizole. Ask your doctor or pharmacist
for more details. Tell your doctor of all prescription and nonprescription medication
you may use, especially:
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